Surface Engineering of Artificial Heart Valves to Using Modified Diamond-Like Coatings

Ali, Nasar; Kousa, Y.; Grácio, J.; Cabral, G.; Sousa, António C.M.; Shokufar, T.; Titus, Elby; Madaleno, J. C.; Ahmed, Waqar; Jackson, Mark J.

doi:10.1007/978-3-319-33489-9_6

Cited by 2 publications

(2 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…DLC coatings have been proposed in the cardiovascular field and claimed as possible functional coatings to improve the hemocompatibility of cardiac and aortic valves. 20 , 21 , 22 , 23 Such coatings did not interfere with the opening performance of the valves; however, the opening dynamics of cardiac/aortic valves are very different from the one featuring the polymeric valve proposed in this study and usable in artificial sphincters. Also, the long‐term stability of DLC coatings was assessed in previous studies, 24 but in very different conditions (without any deformation of the polymeric structure below them).…”

Section: Discussionmentioning

confidence: 69%

“…This is probably the reason for the higher variability in terms of opening pressure during the 4-month fatigue cycles, for the PDMS + DLC valves. DLC coatings have been proposed in the cardiovascular field and claimed as possible functional coatings to improve the hemocompatibility of cardiac and aortic valves [20][21][22][23]. Such coatings did not interfere with the opening performance of the valves; however, the opening dynamics of cardiac/aortic valves are very different fromF I G U R E 3 Fatigue test: SEM images.…”

mentioning

confidence: 99%

See 1 more Smart Citation

PDMS and DLC‐coated unidirectional valves for artificial urinary sphincters: Opening performance after 126 days of immersion in urine

et al. 2021

View full text Add to dashboard Cite

In this work, unidirectional valves made of bare polydimethylsiloxane (PDMS) and PDMS provided with a micrometric diamond-like carbon (DLC) coating were fabricated and characterized, in terms of surface properties and opening pressure. The valve performance was also tested over 1250 repeated cycles of opening/closure in water, finding a slight decrease in the opening pressure after such cycles (10%) for the PDMS valves, while almost no variation for the PDMS + DLC ones. The valves were then immersed in urine for 126 days, evaluating the formation of encrustations and the trend of the opening pressure over time. Results showed that PDMS valves were featured by a thin layer of encrustations after 126 days, but the overall encrustation level was much smaller than the one shown by PDMS in static conditions. Furthermore, the opening pressure was almost not affected by such a thin layer of crystals. DLC-coated valves showed even less encrustations at the same time-point, with no significant loss of performance over time, although they were featured by a higher variability. These results suggest that most encrustations can be removed by the mechanical action of the valve during daily openings/closures. Such a selfcleaning behavior with respect to a static condition opens exciting scenarios for the long-term functionality of mobile devices operating in the urinary environment.

show abstract

Section: Discussionmentioning

confidence: 69%

mentioning

confidence: 99%

PDMS and DLC‐coated unidirectional valves for artificial urinary sphincters: Opening performance after 126 days of immersion in urine

et al. 2021

View full text Add to dashboard Cite

show abstract

Interface properties of nanostructured carbon-coated biological implants: an overview

Bartoli,

Cardano,

Piatti

et al. 2024

Beilstein J. Nanotechnol.

View full text Add to dashboard Cite

The interfaces between medical implants and living tissues are of great complexity because of the simultaneous occurrence of a wide variety of phenomena. The engineering of implant surfaces represents a crucial challenge in material science, but the further improvement of implant properties remains a critical task. It can be achieved through several processes. Among them, the production of specialized coatings based on carbon-based materials stands very promising. The use of carbon coatings allows one to simultaneously fine-tune tribological, mechanical, and chemical properties. Here, we review applications of nanostructured carbon coatings (nanodiamonds, carbon nanotubes, and graphene-related materials) for the improvement of the overall properties of medical implants. We are focusing on biological interactions, improved corrosion resistance, and overall mechanical properties, trying to provide a complete overview within the field.

show abstract

Surface Engineering of Artificial Heart Valves to Using Modified Diamond-Like Coatings

Cited by 2 publications

References 62 publications

PDMS and DLC‐coated unidirectional valves for artificial urinary sphincters: Opening performance after 126 days of immersion in urine

PDMS and DLC‐coated unidirectional valves for artificial urinary sphincters: Opening performance after 126 days of immersion in urine

Interface properties of nanostructured carbon-coated biological implants: an overview

Contact Info

Product

Resources

About