Surface chemistry modification of PDMS elastomers with boiling water improves cellular adhesion

Park, Joong Yull; Ahn, Dongchan; Choi, Yoon Young; Hwang, Chang Mo; Takayama, Shuichi; Lee, Soon Hyuck; Lee, Sang Hoon

doi:10.1016/j.snb.2012.06.096

Cited by 32 publications

(27 citation statements)

References 21 publications

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“…The surface was then tilted to 90° to see if the droplet remains adhered. The wettability of PDMS has been observed to change after boiling in water [42]. We observed that the wettability of PDMS changes significantly within the first hour of boiling and then remains stable.…”

Section: Wetting Characterizationmentioning

confidence: 69%

The petal effect of parahydrophobic surfaces offers low receding contact angles that promote effective boiling

Allred

Weibel

Garimella

2019

International Journal of Heat and Mass Transfer

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Despite extensive study of boiling processes and their widespread use in industry, critical interactions between the fluid and surface during boiling remain poorly understood. Simplistic, static descriptions of the contact angle are still relied upon to describe the effects of surface wettability on dynamic interfacial processes that govern boiling. This work demonstrates the critical role of the dynamic wettability characteristics of a surface on bubble growth dynamics and boiling performance. In spite of their superior nucleation behavior, hydrophobic surfaces have received little attention for boiling applications due to their typically premature transition from efficient nucleate boiling to inefficient film boiling. Evaluation of hydrophobic surfaces with high contact angle hysteresis reveals that the heat transfer efficacy of these surfaces can be exploited in boiling, so long as the receding contact angle of the surface is sufficiently small to mitigate vapor spreading and thereby extend the nucleate boiling regime. A new paradigm of textured boiling surfaces-parahydrophobic surfaces that exhibit the "petal effect" and mimic the wetting behavior of a rose petal-are shown to have untapped potential in boiling applications resulting from highly hydrophobic behavior coupled with low receding contact angles.

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Section: Wetting Characterizationmentioning

confidence: 69%

The petal effect of parahydrophobic surfaces offers low receding contact angles that promote effective boiling

Allred

Weibel

Garimella

2019

International Journal of Heat and Mass Transfer

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“…To take advantage of the optical properties of PDMS for microscopy [ 23 ] and enable imaging of the forming tubules during culture inside the PDMS scaffold, the thickness of the bottom layer was maintained around 20 μm. Scaffold hydrophobicity was preserved to avoid cellular attachment [ 24 , 25 ] and facilitate tissue recovery from scaffolds. Scaffolds were re-used multiple times after standard sterilization.…”

Section: Methodsmentioning

confidence: 99%

Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

et al. 2018

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The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made 3D tubules with typical renal epithelial properties. This system was successfully employed to engineer patient-specific tubules, to model polycystic kidney disease (PKD) and test drug efficacy, and to identify a potential new pharmacological treatment. By optimizing our system we constructed functional ureteric bud (UB)-like tubules from human induced pluripotent stem cells (iPSCs), and identified a combination of growth factors that induces budding morphogenesis like embryonic kidneys do. Finally, we applied this assay to investigate budding defects in UB-like tubules derived from a patient with a PAX2 mutation.Our system enables the modeling of human kidney disease and development, drug testing and discovery, and lays the groundwork for engineering anatomically correct kidney tissues in vitro and developing personalized medicine applications.

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“…Regarding the wetting properties, as previously discussed in 3.6., the advancing and receding water contact angles of the coatings can reveal some chemical reorganizations of the surface according to the contact angle hysteresis Δθ w (Δθ w = θ w,adv -θ w,rec ). In the literature, this contact angle hysteresis is either explained by a surface roughness, or by a chemical heterogeneity of the surface, or by the ability of functional groups to reorganize on the surface during contact with the liquid [49][50][51][52]. In this study, the dynamic contact angles were measured after different immersion times to assess the surface reconstruction of the coatings.…”

Section: Surface Free Energy and Wetting Properties Of The Pdms/polyementioning

confidence: 98%

Water erodible coatings based on a hydrolyzable PDMS/polyester network

Gevaux

Lejars

Margaillan

et al. 2018

Materials Today Communications

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HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Surface chemistry modification of PDMS elastomers with boiling water improves cellular adhesion

Cited by 32 publications

References 21 publications

The petal effect of parahydrophobic surfaces offers low receding contact angles that promote effective boiling

The petal effect of parahydrophobic surfaces offers low receding contact angles that promote effective boiling

Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

Water erodible coatings based on a hydrolyzable PDMS/polyester network

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