Surface chemistry, charge and ligand type impact the toxicity of gold nanoparticles to Daphnia magna

Abstract

Using highly characterized gold nanoparticles this study determined that ligand identity, nanoparticle surface charge and aggregation type alters toxicity of gold nanoparticles to Daphnia magna.

Behavior and chronic toxicity of two differently stabilized silver nanoparticles to Daphnia magna

“…Attachment to the carapax has been reported for several NPs with different core materials and coatings (Asghari et al, 2012;Baumann et al, 2014a;Bozich et al, 2014;Dabrunz et al, 2011;Zhao and Wang, 2012). In most cases, it caused reduction or even inhibition of molting (Baumann et al, 2014a;Bozich et al, 2014;Dabrunz et al, 2011) which was not the case in the present study indicating low levels of attachment of the AgNPs to the exoskeleton here.…”

“…5 No general trends were reported for other properties such as hydrophilicity of the stabilizers or presence/absence of certain reactive groups in the coatings (Kim et al, 2013;Levard et al, 2012). In addition, the stabilizer itself changed the toxicity as well as the mode of action of the investigated nanoparticles in other experimental studies (Baumann et al, 2014a;Bozich et al, 2014;Dominguez et al, 2015).…”

Effects of surface charges of gold nanoclusters on long-term in vivo biodistribution, toxicity, and cancer radiation therapy

“…18,19 The dimension, shape, surface charge, and coating can all contribute to the overall toxicity of NPs. [20][21][22][23] To exploit realistic applications of Au NCs, all these factors should be taken into account and studied carefully to ensure the potential side effects on humans are minimized. Various in vitro studies were performed but with conflicting results.…”

A comparison of fate and toxicity of selenite, biogenically, and chemically synthesized selenium nanoparticles to zebrafish (Danio rerio) embryogenesis

“…Recently, Gilbertson et al (2015) reported that surface charge of multi-walled carbon nanotube has the greatest influence on the zebrafish mortality. Several other studies elucidated that the surface charge plays an important role in the observed toxicity trends of nanomaterials using either Daphnia magna or embryonic zebrafish as the in vivo model organisms, which is hypothesized to be governed primarily by the electrostatic interaction between the material and model organism (Bozich et al, 2014;Lee et al, 2013). Based on the data, it is contended that the presence of EPS increases the colloidal stability of nano-Se and prevents interaction of biogenic Se particles and embryos due to electrostatic repulsion (Buchs et al, 2013;Lin et al, 2012).…”