Surface and micellar properties of new nonionic gemini aldonamide-type surfactants

Komorek, Urszula; Wilk, Kazimiera A.

doi:10.1016/j.jcis.2003.09.020

Cited by 57 publications

(39 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2C 10 Glu and 2C 12 Glu formed small aggregates like micelles at low concentrations, as was the case for 2C 10 Lac and 2C 12 Lac; as the aggregates grew, their sizes increased with increasing concentration. Cryogenic transmission electron microscopy cryo-TEM of the aggregates showed that they transformed into rod-like micelles.…”

Section: Aggregation Propertiessupporting

confidence: 51%

“…Similar to conventional monomeric surfactants, the I 1 /I 3 ratio of 2C 8 Lac decreased at a concentration around the cmc obtained by the surface tension measurements and reached approximately 1.2 when the concentration was 10 times the cmc. For 2C 10 Lac and 2C 12 Lac, the I 1 /I 3 ratio started to decrease slowly at concentrations around or above the cmc and reached approximately 1.2 when the concentration was 50-100 times the cmc. This behavior differed from that of 2C 8 Lac and conventional monomeric surfactants.…”

Section: Aggregation Propertiesmentioning

confidence: 94%

“…Although many papers pertaining to the synthesis and properties of cationic and anionic gemini surfactants have been published, there are very few studies on nonionic and zwitterionic gemini surfactants. The majority of the conventional nonionic surfac-that the surface tension decreased in the order 2C 16 peLac 2C 12 peLac 2C 8 Glu 2C 10 Glu 2C 12 Glu. Our results showed that the introduction of a long alkyl chain and a bulky spacer rendered the surfactant less surface active.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Equilibrium Surface Tension, Dynamic Surface Tension, and Micellization Properties of Lactobionamide-Type Sugar-Based Gemini Surfactants

et al. 2013

View full text Add to dashboard Cite

Section: Aggregation Propertiessupporting

confidence: 51%

Section: Aggregation Propertiesmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Equilibrium Surface Tension, Dynamic Surface Tension, and Micellization Properties of Lactobionamide-Type Sugar-Based Gemini Surfactants

et al. 2013

View full text Add to dashboard Cite

“…(3-gluconylamido) propyl]ethylene diamine (bis(C12GA)) (structures are shown in Fig. 1) (24,25). Using different types of surfactant architectures to form o/w microemulsions offers the flexibility to choose the microemulsion template that provides optimal loading, release and biological impact in the cell environment.…”

Section: Photo-oxidative Action In Mcf-7 Cancer Cells Induced By Hydrmentioning

confidence: 99%

Photo-oxidative action in MCF-7 cancer cells induced by hydrophobic cyanines loaded in biodegradable microemulsion-templated nanocapsules

et al. 2012

View full text Add to dashboard Cite

Abstract. Searching for photodynamic therapy-effective nanocarriers which enable a photosensitizer to be selectively delivered to tumor cells with enhanced bioavailability and diminished dark cytotoxicity is of current interest. We have employed a polymer-based nanoparticle approach to encapsulate the cyanine-type photosensitizer IR-780 in poly(n-butyl cyanoacrylate) (PBCA) nanocapsules. The latter were fabricated by interfacial polymerization in oil-in-water (o/w) microemulsions formed by dicephalic and gemini saccharide-derived surfactants. Nanocarriers were characterized by SEM, AFM and DLS. The efficiency of PBCA nanocapsules as a potential system of photosensitizer delivery to human breast cancer cells was established by dark and photocytotoxicity as the function of the cellular mitochondria. The photodynamic effect of cyanine IR-780 was determined by investigation of oxidative stress markers. The nanocapsules were the main focus of our studies to examine their cellular uptake and dark and photocytotoxicity as the function of the cellular mitochondria as well as oxidative stress markers (i.e., lipid peroxidation and protein damage) in MCF-7/WT cancer cells. The effects of encapsulated IR-780 were compared with those of native photosensitizer. The penetration of the nanocapsules into cancer cells was visualized by CLSM and their uptake was estimated by FACS analysis. Cyanine IR-780 delivered in PBCA nanocapsules to MCF-7/ WT cells retains its sensitivity upon photoirradiation and it is regularly distributed in the cell cytoplasm. The intensity of the photosensitizer-generated oxidative stress depends on IR-780 release from the effective uptake of polymeric nanocapsules and seems to remain dependent upon the surfactant structure in o/w microemulsion-based templates applied to nanocapsule fabrication.

show abstract

“…This paper deals with the small angle scattering study of the micellization of nonionic gemini surfactant bis(C12LA) [7,8]. We have studied the eect of concentration and temperature on the structure of isotropic so- for monodisperse particles by [13]:…”

Section: Introductionmentioning

confidence: 99%

Structure of Dilute Micellar Water Solutions of Nonionic Dimeric Surfactant Study by Small Angle Neutron Scattering Method

Rajewska

Wilk

2014

Acta Phys. Pol. A

View full text Add to dashboard Cite

show abstract

Surface and micellar properties of new nonionic gemini aldonamide-type surfactants

Cited by 57 publications

References 29 publications

Equilibrium Surface Tension, Dynamic Surface Tension, and Micellization Properties of Lactobionamide-Type Sugar-Based Gemini Surfactants

Equilibrium Surface Tension, Dynamic Surface Tension, and Micellization Properties of Lactobionamide-Type Sugar-Based Gemini Surfactants

Photo-oxidative action in MCF-7 cancer cells induced by hydrophobic cyanines loaded in biodegradable microemulsion-templated nanocapsules

Structure of Dilute Micellar Water Solutions of Nonionic Dimeric Surfactant Study by Small Angle Neutron Scattering Method

Contact Info

Product

Resources

About