In order to examine temperature changes and extremes in the Beijing-Tianjin Sand Source Region (BTSSR), ten extreme temperature indices were selected, categorized, and calculated spanning the period 1960-2014, and the spatiotemporal variability and trends of temperature and extremes on multitimescales in the BTSSR were investigated using the Mann-Kendall (M-K) test, Sen's slope estimator, and linear regression. Results show that mean temperatures have increased and extreme temperature events have become more frequent. Annual temperature has recorded a significant increasing trend over the BTSSR, in which 51 stations exhibited significant increasing trends ( < 0.05); winter temperature recorded the most significant increasing trend in the northwest subregion. All extreme temperature indices showed warming trends at most stations; a higher warming slope in extreme temperature mainly occurred along the northeast border and northwest border and in the central-southern mountain area. As extreme low temperature events decrease, vegetation damage due to freezing temperatures will reduce and low cold-tolerant plants may expand their distribution range northward to revegetate barren areas in the BTSSR. However, in water-limited areas of the BTSSR, increasing temperatures in the growing season may exacerbate stress associated with plants relying on precipitation due to higher temperatures combining with decreasing precipitation.