2014
DOI: 10.1146/annurev-fluid-010313-141418
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Surface Acoustic Wave Microfluidics

Abstract: Fluid manipulations at the microscale and beyond are powerfully enabled through the use of 10-1,000-MHz acoustic waves. A superior alternative in many cases to other microfluidic actuation techniques, such high-frequency acoustics is almost universally produced by surface acoustic wave devices that employ electromechanical transduction in wafer-scale or thin-film piezoelectric media to generate the kinetic energy needed to transport and manipulate fluids placed in adjacent microfluidic structures. These waves … Show more

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Cited by 478 publications
(343 citation statements)
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“…Recently, there has been increased interest in surface acoustic wave (SAW) based microfluidics (often called acoustofluidics) and biosensors due to their promising applications in the fields of lab-on-a-chip and point of care diagnosis [13][14][15][16][17][18]. For these applications, it is essential to develop strategies for reliable and efficient microfluidic functions and manipulation of particles and bio-molecules in the liquid, such as in a droplet-digital microfluidics [19][20][21].…”
Section: Acoustofluidicsmentioning
confidence: 99%
“…Recently, there has been increased interest in surface acoustic wave (SAW) based microfluidics (often called acoustofluidics) and biosensors due to their promising applications in the fields of lab-on-a-chip and point of care diagnosis [13][14][15][16][17][18]. For these applications, it is essential to develop strategies for reliable and efficient microfluidic functions and manipulation of particles and bio-molecules in the liquid, such as in a droplet-digital microfluidics [19][20][21].…”
Section: Acoustofluidicsmentioning
confidence: 99%
“…9 Most acoustofluidic particle manipulation devices utilise standing wave fields, and the acoustic streaming field is generally dominated by boundary-driven streaming which arises from the acoustic attenuation within the acoustic boundary layer due to the non-slip condition on the walls of the fluid channel. Another significant streaming pattern, Eckart streaming, 10 requires acoustic absorption over longer distances (as is the case in surface acoustic wave devices 11,12 ) than those found in these bulk acoustic wave resonators. Experimental observation and modelling of surface acoustic wave devices by Tan et al 13 reveal a rich pattern of streaming vortices in such devices.…”
Section: Introductionmentioning
confidence: 97%
“…Centrifugal-based microfluidics 5 can drive fluidic routing, mixing, and metering on rotating substrates with on-chip valves and channels, but the motor required for actuation is expensive, and this platform lacks flexibility; the spinning chip cannot be interfaced with external electrical readouts or sensors. Platforms based on SAW 12 and electrical forces 13 offer an effective means to transport liquid on-chip, but require expensive and often large electrical equipment. In terms of developing microfluidic systems for point-of-care diagnostics, personalized medicine, and environmental monitoring, developing more portable fluidic manipulation technology is an important step for reaching this goal.…”
Section: Introductionmentioning
confidence: 99%