Surenone and surenin, two novel tetranortriterpenoids from Toona sureni [blume] merrill.

Kraus, Wolfgang; Kypke, Karin

doi:10.1016/s0040-4039(01)86395-4

Cited by 27 publications

(24 citation statements)

References 4 publications

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“…The results showed that compounds 1−22 exhibited inactivation effects at 50 μg/mL against tobacco mosaic virus (TMV) replication ranging from 21.2% to 98.2%. Compounds 2, 8,9,10,11,12,18, and 20 showed greater inhibition rates than that of the positive control, ningnanmycin (58.9%). The effects of compounds 1−22 at a concentration of 200 μg/mL were tested, and the results showed that all of the compounds exhibited inhibitory activities against TMV.…”

Section: ■ Results and Discussionmentioning

confidence: 89%

“…The effects of compounds 1−22 at a concentration of 200 μg/mL were tested, and the results showed that all of the compounds exhibited inhibitory activities against TMV. At this same concentration, compounds 2, 8,9,11,12,16, and 18 showed the most potent antiviral activities. In addition, the protective effects of all the compounds were also evaluated at a concentration of 200 μg/mL.…”

Section: ■ Results and Discussionmentioning

confidence: 91%

“…In addition, the protective effects of all the compounds were also evaluated at a concentration of 200 μg/mL. The results showed that compounds 2, 8,9,11,12, and 16 showed protective effects. The IC 50 values of the eight compounds were determined and are listed in Table 7, with ningnanmycin as the positive control.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…All compounds were evaluated for their antitobacco mosaic virus (TMV) activity and in vitro cytotoxicity against the human cancer HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. Among them, compounds 2,8,9,10,11,12,18, and 20 showed significant anti-TMV activity, with IC 50 values in the range 19.6−44.4 μg/mL. Compounds 1 and 18 exhibited cytotoxic effects for all five cancer cell lines, with IC 50 values between 0.4 and 4.8 μM.…”

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confidence: 99%

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Bioactive Limonoid Constituents of Munronia henryi

et al. 2015

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Fourteen new limonoids, munronins A-N (1-14), and eight known limonoids (15-22) were isolated from the whole plants of Munronia henryi. The structures of the new compounds were elucidated by 2D NMR spectroscopy and mass spectrometry, and the structure of 8 was confirmed by single-crystal X-ray diffraction analysis. Compound 1 represents the first limonoid found with a novel 7-oxabicyclo[2.2.1]heptane moiety produced by incorporating C-11 and C-14 via an oxygen atom. All compounds were evaluated for their anti-tobacco mosaic virus (TMV) activity and in vitro cytotoxicity against the human cancer HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. Among them, compounds 2, 8, 9, 10, 11, 12, 18, and 20 showed significant anti-TMV activity, with IC50 values in the range 19.6-44.4 μg/mL. Compounds 1 and 18 exhibited cytotoxic effects for all five cancer cell lines, with IC50 values between 0.4 and 4.8 μM.

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Section: ■ Results and Discussionmentioning

confidence: 89%

Section: ■ Results and Discussionmentioning

confidence: 91%

Section: ■ Results and Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Bioactive Limonoid Constituents of Munronia henryi

et al. 2015

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“…The literature search revealed that a number different compounds have previously been isolated from the leaves of the plant, including tetranortriterpenoid (surenin, surenone and surenolactone) [13,14] , and carotenoids [15][16] .…”

Section: Introductionmentioning

confidence: 99%

CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF THE ESSENTIAL OIL OF THE Toona sureni (Blume) Merr

Ekaprasada¹,

Nurdin²,

Ibrahim³

et al. 2015

J.Ris.Kim.

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The essential oil composition of the Toona sureni (Blume) Merr leaf was analyzed by GC-MS. More than 68 peaks, representing 99.99% of total oil, forty three components were identified, this represents 80.65% of the total oil component. The major components were α-terpinene (9.58%), α-copaene (8.39%), bicyclogermacrene (7.61%), δ-cadinene (6.65%), β-elemene (4.88%), germacrene-D (4.65%), δ-selinene (3.58%), caralene (3.10%), β-caryophyllene (2.88%), α-cubebene (2.82%), δ-gurjunene (2.20%), and (-)-isoledene (2.05%). The antibacterial activity of the essential oil of Toona sureni (Blume) Merr leaf was evaluated using disk diffusion method. The oil was effective on the inactivation of Escherichia coli, Staphylococcus aureus and Bacillus subtilis.

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Four New Limonoids from Aphanamixis grandifolia

Tong¹,

Yu²,

He³

et al. 2012

Chin. J. Chem.

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Four new limonoids, named aphanagranins A–D (1–4), were isolated from the fruits of Aphanamixis grandifolia. The new structures were determined by spectroscopic methods especially 1D and 2D NMR analysis. Aphanagranin A (1) possessed a rare four membered oxygen heterocyclic ring and its absolute configurations were determined on the basis of the signal crystal X‐ray diffraction analysis. Furthermore, compounds 1 and 2 showed weak activity toward brine shrimp (Artemia salina).

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Surenone and surenin, two novel tetranortriterpenoids from Toona sureni [blume] merrill.

Cited by 27 publications

References 4 publications

Bioactive Limonoid Constituents of Munronia henryi

Bioactive Limonoid Constituents of Munronia henryi

CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF THE ESSENTIAL OIL OF THE Toona sureni (Blume) Merr

Four New Limonoids from Aphanamixis grandifolia

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