Supratentorial intracerebral schwannomas

Gökay, H; İzgi, Nail; Barlas, Orhan; Erseven, Gülçin

doi:10.1016/0090-3019(84)90232-5

Cited by 38 publications

(7 citation statements)

References 4 publications

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“…Fewer than 40 cases have been reported in the English‐language literature since the first case reported by Gibson et al . in 1966 2–25 . In these, 27 cases were reported with the histological diagnosis being confirmed by either immunohistochemical staining or electron microscopic examination, or both 2–8,10–16,19–21 …”

Section: Discussionmentioning

confidence: 99%

Intracerebral schwannoma clinically and radiologically mimicking meningioma

Takei

Schmiege

Buckleair

et al. 2005

Pathology International

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A case of intracerebral schwannoma (ICS) occurring in a 33-year-old woman is presented. The patient's history of headache, numbness, tingling and the recent development of weakness of the right upper extremity with right facial droop began during pregnancy. Magnetic resonance imaging (MRI) showed a 4 x 2 x 2 cm heterogeneous, gadolinium-enhanced mass at the left frontoparietal junction, with peritumoral edema and a dural-based attachment. During her pregnancy, the mass increased in size. The surgically resected specimen consisted of lobulated, somewhat gelatinous soft tissue. Microscopically, the tumor demonstrated classic biphasic Antoni type A and B patterns, admixed with degenerative changes. Immunohistochemically, the neoplastic cells were positive for S-100 protein (diffuse and strong), CD34 (primarily in Antoni B areas), glial fibrillary acidic protein (GFAP; weak and diffuse) and calretinin (mainly in Antoni A areas), while none was positive for CD31, estrogen and progesterone receptors, bcl-2, or epithelial membrane antigen (EMA). Ultrastructurally, basal laminae and Luse bodies were identified. The differential diagnosis includes fibrous meningioma, solitary fibrous tumor, and ICS. Twenty-seven cases of ICS were reviewed in which the histological diagnosis was confirmed immunohistochemically or ultrastructually, and the cases were summarized (including the present case). A combined use of immunostains (S-100 protein, EMA, CD34, and maybe calretinin) is of great help in distinguishing ICS from its histological mimickers.

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Section: Discussionmentioning

confidence: 99%

Intracerebral schwannoma clinically and radiologically mimicking meningioma

Takei

Schmiege

Buckleair

et al. 2005

Pathology International

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“…Although many theories for the origin of these tumours have been proposed, the origin has not been clarified, since Schwann cells are not typically found in the CNS [1,2,4,7,11].…”

Section: Discussionmentioning

confidence: 99%

“…The tumours are extremely rare in patients under the age of 15 years [8,9]. The origin of these tumours is still not clear [1,2,4]. Intraparenchymal schwannomas of the brain and spinal cord are rare.…”

Section: Introductionmentioning

confidence: 99%

Schwannoma of the Lateral Ventricle: Eight-Year Follow-Up and Literature Review

Erdoğan¹,

Öngürü²,

Bulakbaşı³

et al. 2003

Minim Invasive Neurosurg

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Intracerebral and intramedullary schwannomas are uncommon; but, in general, spinal intramedullary schwannomas are more frequent than intracerebral schwanomas. We present a case of right lateral ventricle schwannoma in a 21-year-old man and review the associated literature. The 21-year-old right-handed man presented with loss of the left-eye vision approximately 8 months before referral to an ophthalmologist. The patient was immediately subjected to computed tomography (CT) scan, which showed an enhanced lesion with cystic component in the right occipital horn of the lateral ventricle. And consecutively, he was admitted to our department. The tumor was evacuated via craniotomy with marked improvement in his clinical state. The postoperative course was uneventful and postoperative CT control showed no residue. On MRI control no recurrence was noted after a follow-up period of 8 years. Intracerebral schwannoma is a rare, benign neoplasm. It is usually located superficially or adjacent to a ventricle. Characteristic imaging features include cyst formation, calcification, and evidence of peritumoral edema or gliosis. The recognition of this benign and potentially curable neoplasm and its differentiation from other neoplasms, some of which have less favourable outcomes, is of obvious importance.

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“…8,13,16,33,35 Most reported cases have been seen in children or young adults. 1,16,21,22,24,48,50 Cases occurring in adults beyond the 3rd decade of life have been reported. 28,31 There appears to be no sex predilection in cases of intracerebral schwannoma.…”

Section: Discussionmentioning

confidence: 99%

Intracerebral schwannomas: a rare disease with varying natural history

Scott

Koral²,

Margraf

et al. 2013

PED

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Although intracerebral schwannomas are typically regarded as benign intracranial tumors, malignancy and recurrence have been reported among patients harboring such neoplasms. The available literature consists of case reports and small series that present variable characteristics distinguishing these unusual lesions. Little advancement has been made to further the understanding and management of these tumors. The authors present 3 cases from their institution that highlight the difference between typical benign intracerebral schwannomas and histopathological variants that may portend more aggressive behavior. Also provided is a review of the literature in the hope of gaining a better understanding of these rare tumors.

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Supratentorial intracerebral schwannomas

Cited by 38 publications

References 4 publications

Intracerebral schwannoma clinically and radiologically mimicking meningioma

Intracerebral schwannoma clinically and radiologically mimicking meningioma

Schwannoma of the Lateral Ventricle: Eight-Year Follow-Up and Literature Review

Intracerebral schwannomas: a rare disease with varying natural history

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