Supramolekulare organisch‐anorganische Hybridaggregate mit variabler Partikelgröße: Zusammenspiel von drei nichtkovalenten Wechselwirkungen

Abstract

Gegensätze ziehen sich an: Gold‐ oder CdS‐Nanopartikel und ionische Farbstoffmoleküle können supramolekulare Aggregate mit einer definierten Größe zwischen 100 und 300 nm bilden, wenn man ein Makroion als Templat und Bindeglied verwendet. Das Bild zeigt das erhaltene Gold‐Dendrimer‐Farbstoff‐Aggregat (blaue Kugeln: dendritisches Makroion, rote Kugeln: Gold, rote Balken: ionischer Farbstoff).

Fabrication of Multiresponsive Bioactive Nanocapsules through Orthogonal Self‐Assembly

“…[8] These supramolecular structures are generated through programmed self-assembly of building blocks (e.g., synthetic materials and biomolecules) by using a broad palette of available noncovalent interactions, including hydrogen bonding, hydrophobic interactions and electrostatic affinities to induce biomimetic assembly. [9] Recent examples of this bioinspired assembly strategy include hybrid assemblies, [ 10 ] peptide amphiphile vesicles [ 11 ] and protocell models. [12] …”

“…synthetic materials and biomolecules) by using a broad palette of available noncovalent interactions, including hydrogen bonding, hydrophobic interactions, and electrostatic affinities to induce biomimetic assembly. [9] Recent examples of this bio-inspired assembly strategy include hybrid assemblies, [10] peptide amphiphile vesicles, [11] and protocell models. [12] The integration of nanoparticles (NPs) into supramolecular structures provides access to the physical [13] and structural [14] properties of the particles.…”

Fabrication of Multiresponsive Bioactive Nanocapsules through Orthogonal Self‐Assembly

“…Here we present the fabrication of multifunctional nanoparticle-stabilized capsules (NPSCs) by using a set of orthogonal supramolecular interactions. [9] Recent examples of this bio-inspired assembly strategy include hybrid assemblies, [10] peptide amphiphile vesicles, [11] and protocell models. These anionic assemblies interact laterally with cationic gold nanoparticles that are anchored to the fatty acid core through guanidinium-carboxylate interactions.…”

“…Several construction challenges, however, must be addressed for these systems to be useful, such as control over the size, stability, and dynamic properties. [9] Recent examples of this bio-inspired assembly strategy include hybrid assemblies, [10] peptide amphiphile vesicles, [11] and protocell models. [7] However, these building elements are fixed, thus making it difficult to further modulate the structure and provide stimuli responsiveness.…”

“…[7] However, these building elements are fixed, thus making it difficult to further modulate the structure and provide stimuli responsiveness. [9] Recent examples of this bio-inspired assembly strategy include hybrid assemblies, [10] peptide amphiphile vesicles, [11] and protocell models. [8] These supramolecular structures are generated through programmed self-assembly of building blocks (e.g.…”