Supramolecular structures from dendrons and dendrimers

Synthesis, Characterisation and in vitro Anti‐Angiogenic Potential of Dendron VEGF Blockers

“…[9] Although dendrimers can be obtained from various types of monomers, poly(e-lysine) dendrimers have particularly been considered in the biomedical field both as protein scaffolds and as carriers for gene, drug and magnetic resonance imaging (MRI) contrast agent delivery. [10,11] More recently, a systemic anti-angiogenic activity of cationic poly(L-lysine) dendrimers has been shown to reduce tumour growth in vivo. [12] However, this activity FF G3K (WHLPFKC) 16 13 101 >90…”

Synthesis and Evaluation of Pegylated Dendrimeric Nanocarrier for Pulmonary Delivery of Low Molecular Weight Heparin

“…The potential use of dendrimers in drug delivery and their unique chemical and physical properties have recently been reviewed (1)(2)(3)(4)(5)(6)(7)(8). To serve as a drug carrier, dendrimers interact with a drug molecule by a number of mechanisms: (1) Drugs can be encapsulated within dendrimeric cavities, where they may be retained by physical entrapment, electrostatic interactions, hydrophobic or hydrogen bonding; (2) Drugs can also be bound to the surface of the dendrimer by electrostatic or covalent interactions.…”

Self-assembling amphiphilic Janus dendrimers: mesomorphic properties and aggregation in water

“…The thermal and structural data are gathered in Table 1. Since several reports in bibliography show the ability of dendritic wedges to form liquid crystal mesophases, [33][34] also the thermal behavior of the starting 60 lipophilic and hydrophilic dendron was studied; none of them shows liquid crystalline behavior (see Table S4-2 in the ESI). POM observation of the final Janus dendrimers indicated mesomorphic behavior for G 1 (C17) 2 -G 3 (OH) 8 , G 2 (C17) 4 -G 2 (OH) 4 , G 2 (C17) 4 -G 3 (OH) 8 (Fig.…”