Supramolecular self-assembly between symmetric tetramethyl cucurbit[6]uril and dimethylphenylpiperazine hydrochloride

Hu, Jian-Hang; Yu, Zhi-Chao; Zhang, Jiayi; Liu, Zhi-Nian; Hou, Run-Xin; Xiong, Yu; Redshaw, Carl; Tao, Zhu; Xiao, Xin

doi:10.1016/j.poly.2022.116241

Cited by 1 publication

(1 citation statement)

References 43 publications

(69 reference statements)

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“…[67,68] Supramolecular hydrogels formed based on host-guest interactions usually contain groups such as cyclodextrin, Cucurbit [n] uril, azobenzene, PEG, and adamantane. [69,70] Supramolecular hydrogels based on macrocyclic molecules can generally be divided into two categories: one is the poly(quasi)rotaxane structure formed by threading the host molecule onto a polymer chain, which changes the hydrophilicity/hydrophobicity balance intermolecular hydrogen Cyclodextrin [71,73] PEG [72] Cucurbituril [74] Hydrogen bonding 4-120 UPy [78,82] Amide bond [79] Hydroxyl [81,82] Base pair [83,84] 𝜋-𝜋 stacking 0-50 Pyrene [85] Fluorenyl [86][87][88] Tetrazole [89] Hydrophobic effect…”

Section: Host-guest Interactionsmentioning

confidence: 99%

Bioinspired Supramolecular Hydrogel from Design to Applications

Gao,

Yang,

Song

2023

Small Methods

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Nature offers a wealth of opportunities to solve scientific and technological issues based on its unique structures and function. The dynamic non‐covalent interaction is considered to be the main base of living functions of creatures including humans, animals, and plants. Supramolecular hydrogels formed by non‐covalent bonding interactions has become a unique platform for constructing promising materials for medicine, energy, electronic, and biological substitute. In this review, the self‐assemble principle of supramolecular hydrogels is summarized. Next, the stimulation of external environment that triggers the assembly or disassembly of supramolecular hydrogels are recapitulated, including temperature, mechanics, light, pH, ions, etc. The main applications of bioinspired supramolecular hydrogels in terms of bionic objects including humans, animals, and plants are also described. Although so many efforts are done for revealing the synergized mechanism of the function and non‐covalent interactions on the supramolecular hydrogel, the complexity and variability between stimulus and non‐covalent bonding in the supramolecular system still require impeccable theories. As an outlook, the bioinspired supramolecular hydrogel is just beginning to exhibit its great potential in human life, offering significant opportunities in drug delivery and screening, implantable devices and substitutions, tissue engineering, micro‐fluidic devices, and biosensors.

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