Supramolecular Polymerization Promoted and Controlled through Self‐Sorting

Huang, Zehuan; Yang, Liulin; Liu, Yiliu; Wang, Zhiqiang; Scherman, Oren A.; Zhang, Xi

doi:10.1002/anie.201402817

Cited by 203 publications

(161 citation statements)

References 91 publications

Supporting

Mentioning

160

Contrasting

Order By: Relevance

“…267 Zhang and Sherman reported a supramolecular polymerization promoted through selfsorting, using an Naph-Phen-Naph type monomer, connecting one p-phenylene moiety flanked by two naphthalene derivatives. 268 CB [7] binds selectively to p-phenylene to produce a rigid and bulky linker, whereby the naphthalene end groups become accessible for the formation of intermolecular 2:1 complexation with CB [8], leading to the formation of linear supramolecular polymers. These were characterized by ITC, DOSY-NMR, and asymmetric flow field-flow fractionation (AsF-FFF) coupled to UV, differential refraction and MALS detectors, which showed molecular weights of up to 9.7 3 10 4 g mol 21 with an average DP 5 28 and -D of 1.5.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Controlling supramolecular polymerization through multicomponent self‐assembly

Besenius

2016

J. Polym. Sci. Part A: Polym. Chem.

127

102

View full text Add to dashboard Cite

The self-assembly into supramolecular polymers is a process driven by reversible non-covalent interactions between monomers, and gives access to materials applications incorporating mechanical, biological, optical or electronic functionalities. Compared to the achievements in precision polymer synthesis via living and controlled covalent polymerization processes, supramolecular chemists have only just learned how to developed strategies that allow similar control over polymer length, (co)monomer sequence and morphology (random, alternating or blocked ordering). This highlight article discusses the unique opportunities that arise when coassembling multicomponent supramolecular polymers, and focusses on four strategies in order to control the polymer architecture, size, stability and its stimuli-responsive properties: (1) endcapping of supramolecular polymers, (2) biomimetic templated polymerization, (3) controlled selectivity and reactivity in supramolecular copolymerization, and (4) living supramolecular polymerization. In contrast to the traditional focus on equilibrium systems, our emphasis is also on the manipulation of selfassembly kinetics of synthetic supramolecular systems. V C 2016

show abstract

mentioning

confidence: 99%

“…268 Scherman and coworkers reported photoswitchable supramolecular polymers by developing an AB-type heteroditopic monomer AzoV functionalized with an azobenzene (A) and a bipyridinium (B) guest motif for CB [8], as well as the corresponding ABBA-type monomer AzoVVAzo that connects the rigid azobenzene-bipyridinium unit via a short C 4 -spacer (Fig. 22).…”

mentioning

confidence: 99%

Controlling supramolecular polymerization through multicomponent self‐assembly

Besenius

2016

J. Polym. Sci. Part A: Polym. Chem.

127

102

View full text Add to dashboard Cite

show abstract

“…Since the concept of "supramolecular polymer" was proposed [2], the interest of supramolecular chemistry has been extended from the host-guest recognition interactions to the discovery of polymerization methods and functional materials with different applications, which include stimuli responsiveness, self-healing, and environmental adaptation [3,[118][119][120]. With the development of a series of supramolecular polymerization methods, a variety of novel supramolecular polymers are prepared with various non-covalently interactions [121], including host-guest, metal-ligand, H-bonding, π-π, and charge-transfer interactions.…”

Section: Smfs Studies On the Interactions Involved In Supramolecular mentioning

confidence: 99%

Supramolecular Chemistry and Mechanochemistry of Macromolecules: Recent Advances by Single-Molecule Force Spectroscopy

Cheng

Cui

2015

Topics in Current Chemistry

View full text Add to dashboard Cite

Atomic force spectroscopy (AFM)-based single-molecule force spectroscopy (SMFS) was invented in the 1990s. Since then, SMFS has been developed into a powerful tool to study the inter- and intra-molecular interactions of macromolecules. Using SMFS, a number of problems in the field of supramolecular chemistry and mechanochemistry have been studied at the single-molecule level, which are not accessible by traditional ensemble characterization methods. In this review, the principles of SMFS are introduced, followed by the discussion of several problems of contemporary interest at the interface of supramolecular chemistry and mechanochemistry of macromolecules, including single-chain elasticity of macromolecules, interactions between water and macromolecules, interactions between macromolecules and solid surface, and the interactions in supramolecular polymers.

show abstract

“…[30][31][32][33][34] In recent years, we have developed a series of cucurbit[8]uril(CB[8]) 35 -based supramolecular polymers through supramolecular polymerization of small monomers or covalent polymerization of supramonomers. [19][20][21][22][23][24][25] Although the field of supramolecular polymers has progressed rapidly, 36-42 it is still highly demanded to establish new methods to prepare functional supramolecular polymers.Selenium-containing polymers are a new kind of stimuliresponsive polymers which are sensitive to either oxidants or reductants. 43 The redox responsiveness of selenium-containing polymers is faster and more sensitive compared to that of sulfur-containing polymers.…”

mentioning

confidence: 99%

Amphiphilic diselenide-containing supramolecular polymers

et al. 2015

Self Cite

View full text Add to dashboard Cite

This communication describes the fabrication of diselenidecontaining supramolecular polymers. The diselenide-containing supramolecular polymers were fabricated by equimolarly mixing (FGGC11Se) 2 and CB [8] in aqueous solution driven by host-guest interactions between cucurbit[8]uril (CB[8]) and Phe-Gly-Gly. The amphiphilic diselenide-containing supramolecular polymers could further form aggregates for loading hydrophobic small molecules such as Nile Red and releasing them upon addition of oxidants or reductants. This line of research not only expands the library of selenium-containing polymers, but also offers a new strategy to develop functional supramolecular polymers for drug delivery. Supramolecular polymers are formed by monomers through noncovalent interactions. 1-8 The noncovalent interactions can be multiple hydrogen bonding, 8-10 metal coordination 11-16 and host-guest interactions. [16][17][18][19][20][21][22][23][24][25][26][27][28][29] Owing to the dynamic nature of noncovalent interactions, supramolecular polymers can be a type of promising material with reversible, stimuli-responsive, degradable and self-healing characteristics. [30][31][32][33][34] In recent years, we have developed a series of cucurbit[8]uril(CB[8]) 35 -based supramolecular polymers through supramolecular polymerization of small monomers or covalent polymerization of supramonomers. [19][20][21][22][23][24][25] Although the field of supramolecular polymers has progressed rapidly, 36-42 it is still highly demanded to establish new methods to prepare functional supramolecular polymers.Selenium-containing polymers are a new kind of stimuliresponsive polymers which are sensitive to either oxidants or reductants. 43 The redox responsiveness of selenium-containing polymers is faster and more sensitive compared to that of sulfur-containing polymers. We have developed a series of amphiphilic selenium-containing polymers, which can selfassemble to form micellar structures for drug-delivery vehicles. [43][44][45][46] We are wondering if we can combine selenium chemistry and supramolecular polymeric chemistry to fabricate selenium-containing supramolecular polymers. With the aim to develop a new type of functional supramolecular polymer, the diselenide bond with high sensitivity to redox stimuli has been chosen to be introduced to the supramolecular polymeric system.To this end, we designed and synthesized diselenide-containing bifunctional monomer, (FGGC11Se) 2 , which was confirmed by 1 H NMR, 13 C NMR, 77 Se NMR and ESI-MS. As shown in Scheme 1, the bifunctional monomer has a diselenide bond in the core linking the two undecyl chains flanked by two tripeptides of Phe-Gly-Gly (FGG) as the end groups. The binding constant of the strong and specific host-guest interactions between CB[8] and FGG can be as high as 10 11 , 47 and the interaction was employed to drive the supramolecular polymerization by equimolarly mixing CB[8] and (FGGC11Se) 2 in aqueous solution. Considering that it contains both hydrophilic and hydrophobic segments, the disel...

show abstract

Supramolecular Polymerization Promoted and Controlled through Self‐Sorting

Cited by 203 publications

References 91 publications

Controlling supramolecular polymerization through multicomponent self‐assembly

Controlling supramolecular polymerization through multicomponent self‐assembly

Supramolecular Chemistry and Mechanochemistry of Macromolecules: Recent Advances by Single-Molecule Force Spectroscopy

Amphiphilic diselenide-containing supramolecular polymers

Contact Info

Product

Resources

About