Supramolecular nanozymes based on peptide self-assembly for biomimetic catalysis

Insights on catalytic mechanism of CeO2 as multiple nanozymes

“…In comparison with natural counterparts, nanozymes delivered the unique benefits of the high diversity of structures, cost-effective synthesis, high chemical stability, easy storage, etc. Afterwards, many nanomaterials with various tailorable morphologies, including metals, metal oxides, carbon, metal sulfides, metal organic frameworks, etc., have been developed as nanozymes with many interesting enzyme-like catalytic performance as well as their wide applications [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Recent reviews have well summarized and documented the great progress of diversiform nanozymes, especially on their design, synthesis, and applications for disease diagnosis and treatments.…”

Flexible Recyclable Cellulose Paper Templated Cu‐Doped Polydopamine Membranes with Dual Enzyme‐Like Activity

“…Natural enzymes are characterized by their superior catalytic efficiency as well as regio‐ and stereo‐specificity on account of their flexible three‐dimensional structures. [ 1,2 ] Enzymatic reactions have been widely investigated in research and industrial fields, including food, health, cosmetics, agriculture, energy, etc. [ 3 ] However, the practical applications of enzymes are hampered by their inherent limitations, such as time‐consuming purification, poor stability, and high cost.…”

“…In particular, nanomaterial-based artificial enzymes (nanozymes) have been booming over the past decade and have emerged as the next generation of enzyme mimics. [1,4,6] It is worth mentioning that most of nanozymes still involve a high cost of preparation and they are difficult to be recycled for reuse. [7] From an economic perspective, it is expected that novel artificial enzymes will have extra merits of low cost, ease of storage and transportation, and excellent recyclability beyond that of natural enzymes and existent nanozymes.…”

“…Inspired by the supramolecular structures and compositions of natural enzymes, supramolecular assemblies based on selfassembly and co-assembly of biological building blocks are the most promising candidates for mimicking natural enzymes. [1,8,9] As the primary units and backbone of active sites in natural enzymes, amino acids and peptides have extensively been used as the main biological building blocks for constructing artificial enzymes. [1,6] Akin to amino acids and peptides, dopamine (DA) and its polymer polydopamine (PDA) inspired by the mussel's adhesive proteins have also attracted much attention due to their robust self-assembly ability, excellent adhesiveness, high chemical reactivity, and outstanding photothermal conversion capability.…”

“…[1,8,9] As the primary units and backbone of active sites in natural enzymes, amino acids and peptides have extensively been used as the main biological building blocks for constructing artificial enzymes. [1,6] Akin to amino acids and peptides, dopamine (DA) and its polymer polydopamine (PDA) inspired by the mussel's adhesive proteins have also attracted much attention due to their robust self-assembly ability, excellent adhesiveness, high chemical reactivity, and outstanding photothermal conversion capability. [10][11][12][13] Especially, the abundant catechol groups and amine groups of PDA endow them strong chelating ability to various metal ions, thus providing great possibilities for mimicking metal ion-containing metalloenzyme.…”