Supramolecular complexes based on cyclodextrins

Space filling of permethylated β‐cyclodextrin by volatile hydrophobic and hydrophilic guests in polyethylene glycol

“…The “guest–host” type of complexation was studied in the polyethylene glycol environment with an average molecular mass of 400 (PEG‐400). It is known from the literature that linear polymers of medium polarity, including PEG, are not inclined to form supramolecular structures resembling beads, with the polymer molecule being the thread and cyclodextrins acting as beads . Unsubstituted cyclodextrins are more likely to form “molecular beads.” Thus, polymeric systems containing substituted cyclodextrins have a higher probability that the cavities will remain sufficiently empty for the guest inclusion.…”

“…Model representations from the literature were used to calculate the binding constants and thermodynamic parameters of the process. Since we used a solution of low concentration of Me‐β‐CD in PEG‐400 (0.076 mol/L, 90 °C) and an infinitely small concentration of guests, the stability constant calculation was done based on Equation assuming that the formed complexes had stoichiometric composition 1:1.…”

The influence of the guest cavitations loading degree in fractal nanohybrids GaSe<β-cyclodextrin<FeSO4>> on the current passing and polarization processes. The giant “battery spin” effect at room temperature.

“…The most important among them is the ability of the selective and backward binding of organic, inorganic, biological molecules, forming the complexes of inclusions with the "key-lock" type in this way. The large electron density inside the cavity of β-CD can activate electrons of molecules of "guests", which leads to the changes in the spectral properties of the included molecules as well as the β-CD [9]. Iron (II) sulfate served as a substrate, which is known precursor for the synthesis of nanomagnetite, which cationic component has a large spin magnetic moment.…”

NMR study of supramolecular inclusion complexes of 7-[2-(morpholin-4-yl)ethyl]-3-(2-ethoxyethyl)-3,7-diazabicyclo[3.3.1]nonane with cyclodextrins

“…Cyclodextrins are capable of hydrophobic binding of a guest molecule in their cavity in aqueous medium. Inclusion of active component I into the cavity of a host molecule can increase the substance solubility, improve its bioavailability and physicochemical stability, and protect it from biodegradation by preventing the interaction with the package [3]. Among the recognized drug-encapsulating (cucurbiturils, crown ethers, calixarenes, and others), cyclodextrins [4] are distinguished by a number of advantageous properties.…”