Supramolecular chiral self-assemblies of Gly–Pro dipeptides on metallic fcc(110) surfaces

Abstract

The adsorption of the Glycine-Proline (Gly-Pro) dipeptide has been investigated by surface science complementary techniques on Au(110) and Ag(110), showing some interesting differences both in the chemical form and surface organization of the adsorbed peptide. On Au(110), Gly-Pro mainly adsorbs under a neutral form (COOH/NH2), at low coverage or for short time of interaction ; the surface species become zwitterionic for higher coverage or longer time of interaction. These changes are accompanied by a complete reorganization of the molecules at the surface. On Ag(110), only anionic molecules (COO -/NH2) were detected on the surface ; and only one type of arrangement was observed. These results will be compared to some previously obtained on Cu (110), thus providing a unique comparison of the adsorption of the same di-peptide on three different metal surfaces; the great influence of the substrate on both the chemical form and the arrangement of adsorbed di-peptides was made clear.

Chiral Recognition of Self-Assembled Peptides on MoS2 via Lattice Matching

“…The red and green arrows represent the crystallographic orientations of self-assembled L-M6 and D-M6 peptides, respectively. We found that the chiral index (6,5) is the closest to the red line of L-M6 peptides, based on the relationship between the angle and chiral index (Figure S2). The orientation of the D-M6 peptide ordered nanostructures correspond to a chiral index of (5,6).…”

“…We found that the chiral index (6,5) is the closest to the red line of L-M6 peptides, based on the relationship between the angle and chiral index (Figure S2). The orientation of the D-M6 peptide ordered nanostructures correspond to a chiral index of (5,6). Both the self-assembly of L-M6 and D-M6 peptides have mirror symmetry along the armchair direction.…”

“…It produces their chiral recognition on inorganic surfaces, where the enantiomer in a form of single molecule or its supramolecular assembly specifically recognizes one of the two symmetrical images of the surface lattice. The chiral recognition was demonstrated with relatively small biomolecules, such as monochiral amino acids , and dipeptides − on metal surfaces revealed by scanning tunneling microscopy (STM). More examples about the chiral recognition were studied with synthetic molecules widely in liquid, dry, or vacuum conditions, − and the three-point interaction model was accepted to well understand their chiral recognition, , which originated from the lock-and-key model between two single molecules.…”

Defects on a pyrite(100) surface produce chemical evolution of glycine under inert conditions: experimental and theoretical approaches

“…The change in the chemical functionality of amino acid molecules adsorbed on sputtered surfaces with time has not been previously reported for any other surface. 31,32 During the chemical evolution process, the N 1s peak varies remarkably; the relative intensities of the two components are reversed ( Table 1). A summary of the XPS results, that is, the C 1s, N 1s and O 1s core-level peaks, ratios and component assignments, for the glycine/pyrite (monosulfide-enriched) system obtained at different evolution times under UHV is given in Table 1.…”

Binding and 2D organization of arginine on Cu(1 1 0)

“…Finally, another key parameter that influences the adsorption mode and subsequently the supramolecular assemblies of a given molecule is the chemical nature of the adsorbed species. We have shown recently that it is possible to tune adsorption mode, geometry and supramolecular assemblies of a given molecule by changing its deposition method: from the gas phase or from an aqueous solution [10][11][12]. The latter is achievable if an Electrospray Ionization (ESI) device is employed, instead of a traditional Knudsen cell.…”