Supramolecular assemblies based on crown- and phosphoryl-substituted phthalocyanines and their metal complexes in microheterogeneous media

Abstract

The review is concerned with studies on peculiar features of supramolecular organization of phthalocyanines (Pc) bearing complex-forming substituents (15-crown-5, 2-oxyphenylphosphonic acid residues) in organized aqueous microheterogeneous media based on cationic and anionic surfactants, bile salts (BS) including sodium deoxycholate (SDC), as well as polyelectrolytes and amphiphilic polymers including a phosphate buff er (рН 7.4). Organized, SDC-based fl uorescence-active phthalocyanine-containing hydrogels obtained for the fi rst time are also considered. In vitro accumulation and localization of Pc in human cervical adenocarcinoma cells, HeLa, as well as the photochemical and sensitizing properties of Pc including light cytotoxicity and photoinduced generation of reactive oxygen species were demonstrated taking octa-crown-substituted magnesium phthalocyaninate as an example.

Syntheses, crystal structures, photo-physical properties, antioxidant and antifungal activities of Mg(II) 4,4′-bipyridine and Mg(II) pyrazine complexes of the 5,10,15,20 tetrakis(4–bromophenyl)porphyrin

“…Nature selects metal magnesium for chlorophyll type light harvesting molecules, so that non -redox magnesium helps in the light harnessing process. The magnesium complexes attract much attention mainly due to promising photo -physical properties [27,28], and these properties underlie the interest of the latter as potential photosensitizers [29]. Interestingly, Mg(II) porphyrin can easily bind with N/O-donor ligands to produce both five-and six-coordinate complexes [30][31][32][33][34].…”

Histamine-bound magnesium porphyrins: diverse coordination modes, inhibitory role in photodegradation of chlorophyll a and antioxidant activity

“…7 Several five and six-coordinated magnesium porphyrins are known due to coordination to N and O-donating ligands. 3,[9][10][11][12][13][14][15][16][17] But the coordination of histamine is not known in the literature.…”