2021
DOI: 10.1016/j.ijscr.2021.105720
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Supraclavicular lymph node metastases from distant primary tumors: Case reports and review of the literature

Abstract: Highlights Cervical lymph nodes are a common site of metastases for malignant tumors, most commonly developed from head and neck primary tumors. Isolated supraclavicular lymph nodes should alert the clinician to consider non head and neck primary neoplasm. Careful clinical examination, imaging tools and pathological analysis are necessary to establish an early diagnosis for adequate treatment.

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Cited by 4 publications
(2 citation statements)
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“…However, direct supraclavicular LN (SCLN) involvement from PC without affecting the regional lymphatics is rarely heard of. 3 Breast, lung, and ovary are the other known nonregional primaries reported to metastasize to SCLNs 4 apart from thyroid and larynx. Biopsy remains the gold standard of diagnosis, while 18 F-fluorodeoxyglucose positron emission tomography computed tomography ( 18 FDG-PET/CT) scan has proven to be the most precise tool in detecting LN and occult distant metastases.…”
Section: Introductionmentioning
confidence: 99%
“…However, direct supraclavicular LN (SCLN) involvement from PC without affecting the regional lymphatics is rarely heard of. 3 Breast, lung, and ovary are the other known nonregional primaries reported to metastasize to SCLNs 4 apart from thyroid and larynx. Biopsy remains the gold standard of diagnosis, while 18 F-fluorodeoxyglucose positron emission tomography computed tomography ( 18 FDG-PET/CT) scan has proven to be the most precise tool in detecting LN and occult distant metastases.…”
Section: Introductionmentioning
confidence: 99%
“…[ 3 ] Breast, lung, and ovary are the other known nonregional primaries reported to metastasize to supraclavicular LNs. [ 4 ] apart from the thyroid and larynx. Biopsy remains the gold standard of diagnosis while 18 F-fluorodeoxy-glucose positron-emission computed-tomography ( 18 F-FDG-PET/CT) scan has proven to be the most precise tool in detecting LN and occult distant metastases.…”
Section: Introductionmentioning
confidence: 99%