Supra-molecular synthons based on gold…π(arene) interactions

Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)

“…3, a very similar mode of coordination is found for 1 and 3, which conforms to the norm for structures of this type [43]. However, a variation is noted in 2, where the arene ring is oriented towards the gold atom rather than the O1 atom; intra-and intermolecular Au…π(arene) interactions have been reviewed recently [44]. Such variations have been discussed in some detail in the literature and arise owing to the combination of subtle electronic and steric effects of the P-, Oand N-bound substituents [41].…”

Tricoordinate Coinage Metal Complexes with a Redox‐Active Tris‐(Ferrocenyl)triazine Backbone Feature Triazine–Metal Interactions

“…In the case of triazine, the observed close, intramolecular C 3 N 3 ···M I contacts, combined with the almost perfect centring of the metal (signified by angle g,T able 1) and classified as delocalised M···p(arene) interactions for gold by Tiekink, [17] are still rare. For other,m ore electron-rich arenes, close contacts between (coinage) metals and the ring system have been found to be important structural motifs with potential impact on catalytic activities.…”

“…For other,m ore electron-rich arenes, close contacts between (coinage) metals and the ring system have been found to be important structural motifs with potential impact on catalytic activities. [17,18] Even though 1,3,5-triazine has recently been recognised as ah ybrid system capableo fb inding both cations and anions, [19] only the latter has been exploited in many examples, [20] while the former has mainly been investigated in silico for the alkaline metals. [21] Complexes 1M,r eported here, show the closest C 3 N 3 ···M I distance for both copper(I) and silver(I).…”

A conformational polymorph of Ph3PAu[SC(OEt)=NPh] featuring an intramolecular Au···π interaction

“…These changes are related to the major conformational difference between the two forms of (I), namely a rotation about the C1-S1 bond that places an oxygen (form α) or an aryl ring (form β) in close proximity to the gold atom. It is noted that Au···π(aryl) interactions, occurring both interand intra-molecularly in crystal structures have been reviewed previously [9,10]. The different conformations in the two forms of (I) are highlighted in Figure 3, and are discussed further below in Computational studies.…”

“…as shown in Figure 1a for I, form α, was replaced by an intramolecular Au···π interaction, e.g. Figure 1b; Au···π interactions are now well-documented in supramolecular chemistry", involving gold(I) centres as well as gold(III) atoms [9,10]. A subsequent study of bipodal analogues of mono-functional thiocarbamide molecules, shown in Figure 1c, resulted in the characterisation of three compounds of the general formula [R 3 PAuSC(OMe)=NC 6 H 4 N=C(OMe)SAuPR 3 ] for R = Et, Cy and Ph [11].…”