Suppression of Pain by Exposure of Acupuncture Points to Polarized Light

Limansky, Yuri; Tamarova, Zinaida A; Gulyar, Sergiy A.

doi:10.1155/2006/784968

Cited by 24 publications

(19 citation statements)

References 30 publications

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“…Analgesia occurred at AP exposition to PL of the diode [14] and halogen nature [1][2][3][4][5][6][7][8][9]. In this case, we confirmed the previously obtained new evidence of PL influence on AP.…”

Section: Discussionsupporting

confidence: 83%

“…Previous studies performed at the Bogomolets Institute of Physiology of NAS of Ukraine, revealed weakening of the somatic pain response under the action of nonpolarized R+IR LED light [13] and polarized halogen light [1][2][3][4][5][6][7][8][9]. The results of the above experiments objectively prove the analgesic effect of polarized R+IR LED light.…”

Section: Discussionsupporting

confidence: 59%

“…Previously performed experimental studies [1][2][3][4][5][6][7][8][9] demonstrated that polychromatic (white) and monochromatic (color) polarized light (PL) during the action on the locus of pain or acupuncture point (AP) evoked statistically significant analgesia. In these studies, the source of polychromatic light was halogen lamp installed in BIOPTRON devices (Zepter, Switzerland) [10,11].…”

mentioning

confidence: 99%

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Analgesic Effects of the Polarized Red+Infrared LED Light

Gulyar¹,

Tamarova²

2017

UCMS

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INTRODUCTION: Our previous studies have shown that exposure of acupuncture points (AP) or painful area of mice to halogen polarized light (PL) effectively weakens the pain. The aim of the study was to determine whether exposure of AP or painful area to LED red-infrared PL evokes analgesic effect. METHODS: The duration of licking the formalin-injected foot (tonic pain) was recorded in control group and mice exposed (5 min, 10 min) to red+infrared LED light on AP E-36 or on the painful area. Power density of the light varied from 0.3 to 16.5 mW/cm 2 . RESULTS: Exposure of AP E-36 or painful area to red-infrared LED PL evoked statistically significant decrease of licking time. The effect depended on the light application duration and its power density. 10-minute light exposition was more effective than 5-minute. The exposure of pain source to LED PL shortened the licking time to 44.1% (at 16.5 mW/cm 2 ) and to 64.4% (at 0.3 mW/cm 2 ). CONCLUSION: The results show the efficacy of pain suppression by exposure of antinociceptive AP or painful area to LED red+infrared PL. The effect depends on the duration of light exposure and its power density.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 59%

mentioning

confidence: 99%

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Analgesic Effects of the Polarized Red+Infrared LED Light

Gulyar¹,

Tamarova²

2017

UCMS

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“…In mice, as in many other mammals, a clearly pronounced marker of pain behavior, licking of the injured limb, can be observed under conditions of the formalin test. According to the duration of episodes of licking (PRRs), we can indirectly but rather convincingly estimate the intensity and duration of pain [16,17].…”

Section: Methodsmentioning

confidence: 99%

Effects of melatonin and antagonists of MT1 and MT2 receptors on somatic pain induced within the fixed circadian rhythm

et al. 2007

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We studied behavioral pain-related reactions (PRRs) induced in mice by subcutaneous injections of 5% formalin within different phases of the fixed circadian illumination rhythm under conditions of administration of exogenous melatonin and of blocking of MT1 and MT2 melatonin receptors. It was demonstrated that modulation of experimentally induced somatic pain depends considerably on the phase of the preset circadian rhythm. In the norm, the duration of PRRs in the middle of the dark phase was 30% smaller than that in the middle of the light phase. Administration of exogenous melatonin in the middle of the light phase decreased the duration of episodes of noxious behavior by 43%, on average. Injections of melatonin within the dark phase resulted in no significant changes in the duration of PRRs. In the dark phase, the blockade of MT1 receptors by luzindole led to an increase in the duration of PRRs by 45%, as compared with the norm, while in the light phase we observed no significant alterations of this duration under conditions of blocking of the above-mentioned receptors. The blockade of MT2 receptors by prazocine in the middle of dark and light phases increased the durations of PRRs by 92 and 28%, respectively. Our data indicate that the analgesic effect of melatonin depends significantly on the level of this hormone in the organism; in turn, such a level is determined by the illumination conditions. The antinoxious effect of melatonin is mediated by MT receptors, in particular by MT2 receptors.

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“…This approach leveled the psycho emotional reactions inherent in man. In experiments on the model of formalin-induced pain in animals, it was proved that when applied to the locus of painful inflammation or to the acupuncture point (AP), PILER-light (PL) caused analgesia [13][14][15][16][17][18][19][20][21]. At equal exposure, the effect significantly depended on the wave range of the light radiation.…”

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confidence: 99%

Untitled

2016

UCMS

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Application of the linear polarized polychromatic and monochromatic low-intensity light on the locus of pain or acupuncture point effectively reduces pain. The purpose of this article is to describe what changes in the analgesic effectiveness of polarized light modified by fullerene or graphene filter will occur. The essence of such a change consists in optimizing the distribution of quanta in the light flux (hyperpolarization). In the model of inflammatory somatic pain (formalin test on mice), we investigated the influence of the BIOPTRON device light, which passed through a fullerene or graphene filter, on the intensity of the pain reaction (licking of the affected limb) and on the painless behavior (sleeping, washing, eating, running) of the examined animals. It was established that a 10-minute application to the inflammation locus or to E-36 acupuncture point of fullerene light caused a significant reduction of pain. Analgesia was 43.5% and 38.5%, respectively. All non-painful behavioral reactions (sleeping, washing, running, eating) increased their duration. Duration of sleep compared with the control increased twice (application of light to the locus of inflammation) and 3 times (application to acupuncture point E-36). Light modified by a layer of graphene, when applied to the point of acupuncture E-36, weakened the pain more than if applied to the inflammation locus. Analgesia was 58.9% and 49.5%, respectively. Among the non-painful behavioral reactions, the most significant changes have undergone sleeping and eating behavior. Duration of sleep compared with the control increased 4 times (locus of inflammation) or 2.35 times (acupuncture point E-36). Comparison of these data with the results obtained for monochromatic polarized light ranges showed that they could be attributed to the most effective group of analgesic light factors. Both fullerene and graphene light, along with analgesic, have a powerful sedative effect, surpassing effects in comparison with all other ranges of polarized light. Polarized polychromatic light of the BIOPTRON device, which has passed through a nanophotonic fullerene or graphene filter, acting onto the pain or acupuncture point E-36, significantly reduces pain and has a sedative effect.

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Suppression of Pain by Exposure of Acupuncture Points to Polarized Light

Abstract: The results show the efficacy of pain suppression by exposure of antinociceptive APs to P light.

Cited by 24 publications

References 30 publications

Analgesic Effects of the Polarized Red+Infrared LED Light

Analgesic Effects of the Polarized Red+Infrared LED Light

Effects of melatonin and antagonists of MT1 and MT2 receptors on somatic pain induced within the fixed circadian rhythm

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