Suppression of Hodgkin???s Disease in a Patient With Cushing???s Syndrome

Abstract

Hodgkin's disease, one of the more common tumors in pediatric oncology, has been shown to be highly responsive to steroids in conjunction with other chemotherapy agents. The authors describe a patient with Cushing's syndrome that suppressed his Hodgkin's disease. He developed constitutional symptoms, and his Hodgkin's disease progressed after the removal of his pituitary tumor. The patient is disease-free following ABVD/MOPP chemotherapy. A high level of steroids before treatment, albeit endogenous, did not preclude successful treatment of Hodgkin's disease. The effect of Cushing's syndrome on Hodgkin's disease has not been previously reported.

Cushing's syndrome can precipitate diabetes but mask non‐Hodgkin's lymphoma

“…We speculate that lymphoma progression was suppressed by the coexistent steroid‐producing adrenal tumour. The decision to treat the non‐Hodgkin's lymphoma was, in part, based on reports of progression of haematological disease following treatment of Cushing's syndrome 1 , 2 . Although histopathological examination of the tumour revealed some features suggestive of adrenocortical carcinoma, the distinction between adenoma and carcinoma can be difficult.…”

The Basic Documentation for Psycho-Oncology Short Form (PO-Bado SF)-an expert rating scale for distress screening: development and psychometric properties

“…Psychosocial distress is common in cancer patients [1,2]. The implementation of distress screening procedures has become firmly established in oncologic treatment today [3]. In Germany, for example, distress screening is one of the certification requirements for Comprehensive Cancer Centers [4].…”