2004
DOI: 10.1016/j.tox.2004.03.018
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Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells

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Cited by 25 publications
(6 citation statements)
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“…An impact of DEHP on calcium signaling and/or myosins was observed in studies involving other cell types than spermatozoa and performed in biological contexts other than reproductive toxicology. DEHP suppressed the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma [46] and induced a decrease in myotube formation in C2C12 cells, associated with reduced MyHC, MyoD and myogenin levels [47]. …”
Section: Discussionmentioning
confidence: 99%
“…An impact of DEHP on calcium signaling and/or myosins was observed in studies involving other cell types than spermatozoa and performed in biological contexts other than reproductive toxicology. DEHP suppressed the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma [46] and induced a decrease in myotube formation in C2C12 cells, associated with reduced MyHC, MyoD and myogenin levels [47]. …”
Section: Discussionmentioning
confidence: 99%
“…Experimental concentrations were chosen according to the literature data. The concentrations used by other authors were in a range between 0.61 µM in SH-SY5Y cells, 1–100 µM in rat neural stem cells, and 200 µM in rat explants of cerebellum (Kasuya 1974; Kaun-Yu et al 2004; Ishido and Suzuki 2014). …”
Section: Methodsmentioning
confidence: 99%
“…Phthalates that include ester groups are described as the most abundant man-made environmental pollutants; they have been used extensively in consumer products and medical devices. 41 They can cause toxicity in many aspects, for example, by binding to estrogen receptors and inducing estrogen receptor-mediated responses. 42 There are also many other features that had been learned and some of them are, to our knowledge, novel.…”
Section: K ) 1 Mmentioning
confidence: 99%