Supporting diagnosis and management of HIV/AIDS patients through point-of-care technology development

McFall, Sally M.; Maiga, Mamoudou; Glucksberg, Matthew R.; Achenbach, Chad J.; Palamountain, Kara L.; Murphy, Robert L.

doi:10.1016/j.cobme.2019.08.009

Cited by 2 publications

(4 citation statements)

References 25 publications

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“…13,14 Point-of-care diagnostics have shown to be a useful tool for improving disease diagnosis and treatment globally. 15,16 Evidence showed POC testing has improved antenatal HIV screening in sub-Sahara Africa. 3 In resourcelimited settings, POC technologies have become reliable and very important by providing healthcare providers with the easiest, most convenient and most accurate way of decision-making on diagnosis and treatment.…”

Section: Introductionmentioning

confidence: 99%

Facilitators and barriers to in vitro diagnostics implementation in resource-limited settings: A scoping review

Ansu-Mensah

Kuupiel

Asiamah

et al. 2023

Afr. j. prim. health care fam. med.

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Low-and middle-income countries.Methods: This scoping review was guided by Arksey and O'Malley's methodological framework. A comprehensive keyword search for literature was conducted in Google Scholar, EBSCOhost, PubMed, Web of Science and ScienceDirect using the Boolean terms ('AND' and 'OR'), as well as Medical Subject Headings. The study considered published articles in the English language from 2016 to 2021 and was limited to qualitative, quantitative and mixed-method studies. Two reviewers independently screened the articles at the abstract and full-text screening phases guided by the eligibility criteria. Data were analysed qualitatively and quantitatively. Results:Of the 57 studies identified through literature searches, 16 met this study's eligibility criteria. Of the 16 studies, 7 reported on both facilitators and barriers; and the remainder reported on only barriers to POC test implementation such as inadequate funding, insufficient human resource, stigmatisation, et cetera. Conclusion:The study demonstrated a wide research gap in facilitators and barriers, especially in the general POC diagnostic test for use in health facilities without laboratories in the LMICs. Extensive research in POC testing service is recommended to improve service delivery.Contribution: This study's findings contribute to a few works of literature on existing evidence of POC testing.

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Section: Introductionmentioning

confidence: 99%

Facilitators and barriers to in vitro diagnostics implementation in resource-limited settings: A scoping review

Ansu-Mensah

Kuupiel

Asiamah

et al. 2023

Afr. j. prim. health care fam. med.

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show abstract

“…With higher limits of detection in POC or self-tests, current research and perspectives on self-testing for VL have discussed this concern regarding lower sensitivities in comparisons to laboratory tests [ 37 ]. Studies of POC VL detection have targeted 1000 copies/mL, the World Health Organization threshold for treatment failure [ 12 , 38 ] in order to achieve high sensitivity compared to centralized laboratory-based assays.…”

Section: Discussionmentioning

confidence: 99%

“…If it was someone who's just monitoring a couple of times a year, then maybe, they got to that point because they were more stable, and we wouldn't need to see it as frequently." (Brooke, Provider) tests [37]. Studies of POC VL detection have targeted 1000 copies/ mL, the World Health Organization threshold for treatment failure [12,38] in order to achieve high sensitivity compared to centralized laboratory-based assays.…”

Section: Sharing Information With Medical Providersmentioning

confidence: 99%

“…Frequency of data report to providers "if it was someone who was needing, for some reason, needing to test very frequently, I wouldn't want to wait a whole year before understanding where their VL was. If it was someone who's just monitoring a couple of times a year, then maybe, they got to that point because they were more stable, and we wouldn ' tests [37]. Studies of POC VL detection have targeted 1000 copies/ mL, the World Health Organization threshold for treatment failure [12,38] in order to achieve high sensitivity compared to centralized laboratory-based assays.…”

Section: Sharing Information With Medical Providersmentioning

confidence: 99%

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Human-centered design of a smartphone-based self-test for HIV viral load monitoring

Rodriguez,

Balian,

Tolliver

et al. 2023

J. Clin. Trans. Sci.

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Background/Objective: HIV viral load self-testing could enable people living with HIV (PLHIV) to monitor their viral suppression status more easily, potentially facilitating medication adherence and safe behavior decision-making. Smartphone-based viral load testing innovations have the potential to reach resource-limited and vulnerable communities to address inequities in access to HIV care. However, successful development and translation of these tests requires meaningful investigation of end-user contexts and incorporation of those context-specific needs early in the design process. The objective of this study is to engage PLHIV and HIV healthcare providers in human-centered design research to inform key design and implementation considerations for a smartphone-based HIV viral load self-testing device prototype in development. Methods: Semi-structured in-depth interviews were conducted with PLHIV (n = 10) and HIV providers (n = 4) in Indiana, a state with suboptimal viral suppression rates and marked disparities in access to HIV care. Interview guides were developed based on contextual investigation and human-centered design frameworks and included a demonstration of the device prototype with feedback-gathering questions. Results: Thematic analysis of interview transcripts revealed important benefits, concerns, and user requirements for smartphone-based HIV VL self-testing within the context of PLHIV lived experience, knowledge, and barriers to care in Indiana. Conclusion: End-user needs and preferences were identified as key design specifications and implementation considerations to facilitate the acceptability and inform ongoing development and ultimately real-world translation of the HIV VL monitoring device prototype.

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Supporting diagnosis and management of HIV/AIDS patients through point-of-care technology development

Cited by 2 publications

References 25 publications

Facilitators and barriers to in vitro diagnostics implementation in resource-limited settings: A scoping review

Facilitators and barriers to in vitro diagnostics implementation in resource-limited settings: A scoping review

Human-centered design of a smartphone-based self-test for HIV viral load monitoring

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