The field of Biomedical engineering has brought two apparently diagonally placed poles of academia of excellence, i.e., field of medicine and the field of state of art engineering science to a closed proximity. Now a day most if not all of the state of art diagnostics in the field of medicine are almost totally dependent upon biomedical signal analysis. Whole of the biological systems are run by nothing but the bio-signals. The process of signal analysis depends upon the types of signals, recording methods, data types, need of compression and portability and possibility of artifacts. The important areas of the clinician's prime concern are the reliability of the data generated, the utility of the data produced in the real clinical settings in making a diagnosis and interference of the diverse type of equipment's signals with each other and its impact upon the final output. Physiologists act as a bridge between the biomedical engineering and the clinician's need assessment and product delivery process.