KHITILOVA EKATERINA. 2017. The Suitability of Expert System Application in Czech Small and Medium-Sized Enterprises. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 65(2): 653-660.Small and medium-sized enterprises play an important role in the economy of Czech Republic. Expert systems are one of the alternatives evaluated the effectiveness of the relationship between supplier and customer. Currently, measurement and increase in efficiency of supplier-customer relations is very topical subject. The requirements for tools the improvement supplier-customer relationship can be specified on the base the literature analysis. The article defines basic requirements for expert system. The presentation of expert system and its suitability in the surroundings of small and medium sized enterprises is the part of this article. The comparison of the expert system possibilities and the compiled requirements leads to suitability analysis of selected solution. Actual questions and the way of future work are derived from current results, presented in the paper. The article defined the directions of development this expert system.