Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency

Abstract

The objective of this study was to compare the effects of &gt;Your&lt; Iron Syrup, a novel oral liquid iron-containing food supplement, with the commonly prescribed iron sulphate (Fe-sulphate) in a mouse model of diet-induced iron deficiency. Standard inbred BALB/cOlaHsd mice were fed low-iron diet for 11 weeks to induce significant decrease in blood haemoglobin and haematocrit and were then supplemented by gavage with either &gt;Your&lt; Iron Syrup or Fe-sulphate for two weeks. In &gt;Your&lt; Iron Syrup group, several markers of iron deficiency, such as serum iron concentration, transferrin saturation and ferritin level were significantly improved in both female and male mice. Fe-sulphate induced similar responses, except that it did not significantly increase iron serum in females and serum ferritin in both sexes. Fe-sulphate significantly increased liver-iron content which &gt;Your&lt; Iron Syrup did not. Transcription of Hamp and selected inflammatory genes in the liver was comparable between the two supplementation groups and with the Control diet group. Some sex-specific effects were noted, which were more pronounced and less variable in males. In conclusion, &gt;Your&lt; Iron Syrup was efficient, comparable and in some parameters superior to Fe-sulphate in improving iron-related parameters without inducing a response of selected liver inflammation markers in a mouse model of diet-induced iron deficiency.

The Effect of Zamzam Water and ProShieldR Varnish on Microhardness of Eroded Primary Enamel Teeth Induced by Ironplus Syrup: An In Vitro Study

“…Oral iron administration is practical, affordable, and generally efficient. 6 Due to their ease of administration, patient compliance with therapy, and ease of quickly modifying dosages throughout treatment based on the pathology and child development, liquid solutions and suspensions are the most suitable ones for use in pediatrics. 7 While the active chemicals in these medications are essential for maintaining or restoring health, some inactive ingredients may be harmful, such as those that promote dental erosion and caries.…”