“…Changes in heart rate, cardiac rhythm and arterial pressure, sweating and vasoconstriction have been reported during anaesthesia and surgery, particularly in patients who have received a myoneural blocking drug. These responses may be reduced or abolished by the use of narcotic supplements (Mushin and Rendell-Baker, 1949;Siker, 1956;Loder, 1957;Davies, 1957;Dundee et al, 1969;Holmes, 1976). However, it has always been difficult to define the clinical indications for giving increments of an analgesic (Siker, 1956;Holmes, 1976).…”