Supplementary Methods, Tables 1 - 3, Figures 1 - 2 from Does Mutated <i>K-RAS</i> Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?

Abstract

&lt;p&gt;Supplementary Table 1. Statistical analysis of endpoints derived from histology. Number of animals in different groups is listed in Figure 1B. Supplementary Table 2. Statistical analysis of adenoma grade by genotypes in the subset of AOM-induced mice, 34 weeks of age, from Table 1B. Number of slides analysed is presented in parentheses. Supplementary Table 3. Analysis of colon ACF by genotypes and treatment. Supplementary Figure 1. Comformation of colon-specific expression of mutant K-Ras allele in the compound Vil-Cre-ERT2K-rasG12D mouse. Supplementary Figure 2. Characterization downstream targets of mutant K-RAS in Vil-Cre-ERT2K-rasG12D mouse model by Western blot analysis in the colon tissue of Control and AOM-treated mice of different genotypes at 26 weeks of age (18 weeks after the last AOM injection when applicable).&lt;/p&gt;