Supplementary Information from Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

Abstract

<p>This file includes extended experimental procedures including 1. Analysis of RNA-sequencing and Cancer Genome Atlas data 2. Generation of shRNA Cell Lines, 3. Automated cell counting, 4. Liquid chromatography and mass spectrometry, 5. BrdU staining of murine tissue; supplementary references and supplementary figure legends</p>