Supplementary Figures 1-4, Supplementary Tables 1-4 from Immunization against HIF-1α Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells <i>In Vivo</i>

Abstract

&lt;p&gt;Supplementary Table 1. Th1/Th2 for eleven epitopes derived from the HIF-1α protein; Supplementary Table 2. Number of tumorigenic implants in the Sca-1positive or Sca-1negative Population; Supplementary Table 3. Complete blood count (median and range) for the indicted immunization. n=4 mice/group; Supplementary Table 4. Serum chemistries (median and range) for the indicted immunization; Supplementary Figure 1. Sca-1positive cells exhibit several stem cell/EMT markers; Supplementary Figure 2. HIF-1α epitope-specific Th respond to naturally processed HIF-1α protein; Supplementary Figure 3. Sca-1positive cells have increased estrogen receptor-alpha (ER-α) gene expression; Supplementary Figure 4. The HIF-1α vaccine does not induce tissue toxicities.&lt;/p&gt;