Supplementary Data from Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells

Abstract

<p>S1. Depletion of RAD52 or FANCD2 in WT HCT116 cells phenocopies R52KO or D2KO cells, respectively. S2. Depletion of MCM4 is relatively inefficient in inducing EdU spot formation in HCT116 cells. S3. The formation of Aph- or siORC1-induced EdU spots depends both on RAD52 and FANCD2 in U2OS cells. S4. The formation of EdU spots depends both on RAD52 and FANCD2 in HeLa cells. S5. Depletion of FANCD2 or RAD52 confers similar cell cycle profiles. S6. EdU spots induced by BRCA2 depletion display the characteristics of mitotic DNA synthesis.</p>