Supplemental Figures from t-Darpp Activates IGF-1R Signaling to Regulate Glucose Metabolism in Trastuzumab-Resistant Breast Cancer Cells

Abstract

<p>Figure S1. Protein levels of PPP1R1B and IGF-1R. Figure S2. Comparison of respiration rates in SK-BR-3 parental and derived cell lines. Figure S3. siRNA knockdown of IGF-1R and IR. Figure S4. The effect of recombinant t-Darpp on oxygen consumption rate (OCR) of SK-BR-3 cells. Figure S5. Western analysis of IGF-1R and Akt phosphorylation in L6 myotubes by treatment with recombinant t-Darpp. Figure S6. Relative endogenous receptor levels in SK-BR-3 and derived cell lines.</p>