Supplemental Figures 1-19 from ROS-Induced CXCR4 Signaling Regulates Mantle Cell Lymphoma (MCL) Cell Survival and Drug Resistance in the Bone Marrow Microenvironment via Autophagy
Abstract:<p>Figure S1: FACS analyses of CXCR4 silenced in Jeko, SP53 and Z138 MCL cells. GFP-positive cells were sorted after infection and CXCR4 expression was evaluated using FACS analyses. 94-74% reduction was noted in all knock down cells. Figure S2: Migration of MCL cells to SDF-1 was effectively decreased after CXCR4 silencing. GFP-positive controls or CXCR4 silenced MCL cells (105) were placed in upper chambers with different concentrations of SDF-1 in lower chambers and the cells were counted in the lower… Show more
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