Supplemental enzymes and probiotics on the gut health of broilers fed with a newly harvested corn diet

Luo, Caiwei; Wang, Liqun; Yuan, Jianmin

doi:10.1016/j.psj.2023.102740

Cited by 4 publications

(4 citation statements)

References 55 publications

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“…The regulation of intestinal tight junctions is mediated by related proteins, such as occludin, claundin-1 and MUC2. Occludin and claudin-1 play an important role in maintaining epithelial cell polarity and regulating intestinal barrier permeability ( 70 ). The up-regulation of occludin may indicate an increase in cell permeability to nutrients, which facilitates the digestion and absorption of nutrients ( 71 ).…”

Section: Discussionmentioning

confidence: 99%

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

Fu,

Zhang,

Huang

et al. 2024

Front. Vet. Sci.

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The purpose of the present study was to investigate the effects of different levels of a Chinese herbal medicine formulation combined with JM113 (CHM-JM113) on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers. The AA broiler chicks were randomly allocated to 5 treatments as follows: a basic diet for the control group, the basic diet supplemented with 0.25% CHM-JM113, 0.5% CHM-JM113, 1% CHM-JM113 and 2% CHM-JM113 for the treatment group, respectively. The results showed that the addition of CHM-JM113 to the diet significantly reduced the mortality (p < 0.01) and improved the European Broiler Index (EBI) (p < 0.05), whereas it had no significance on growth performance of AA broilers (p > 0.05). Comparing the control group, 0.5 and 1% CHM-JM113 group significantly improved the organ index of liver, spleen and bursa (p < 0.05). In terms of intestinal morphology and structure, the addition of different levels of CHM-JM113 increased VH and VH/CD ratio, decreased CD in the small intestine compared to the control group, with 1 and 2% of the additive dose being more effective (p < 0.05). Chinese herbal medicine and probiotics as natural antioxidants also significantly increased the content of SOD in serum of 21-day-old broilers (p < 0.01), and significantly decreased the content of MDA in serum (p < 0.01). At 42 days of age, the addition of 1 and 2% CHM-JM113 significantly increased the content of SOD (p < 0.01) and significantly decreased the content of MDA in the organism (p < 0.01), accompanied by a significant increase in T-AOC and CAT content. In the study of the effect of CHM-JM113 on intestinal immunity, compared with the control group, we found that 1% or 2% CHM-JM113 had a better effect on the expression of occludin and claudin-1 in the intestinal segments of broilers (p < 0.05). For the expression of GATA-3, 0.5% CHM-JM113 may have a better effect (p < 0.05). CHM-JM113 may be used as an antibiotic alternative in broiler production.

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Section: Discussionmentioning

confidence: 99%

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

Fu,

Zhang,

Huang

et al. 2024

Front. Vet. Sci.

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“…Supplementing exogenous digestive enzymes in the diet can improve animal production performance, feed conversion rate and digestion rate, thereby enhancing intestinal immune function [ 27 ] and promoting animal health. Luo et al found that adding protease and glucoamylase to the diet of broiler chickens can significantly increase trypsin activity, increase digestion emptying time and reduce FCR (F/G) and visible water in feces, thereby alleviating diarrhea caused by newly harvested corn diets [ 28 ]. Yi et al reported that adding enzyme complexes containing amylase, protease and xylanase to the diet can improve nutrient digestibility, increase the concentration of volatile fatty acids and the proportion of Escherichia coli, thereby promoting intestinal health and improve piglet production performance [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, Harmful Gas and Heavy Metal Contents in Faeces of Fatteners

Deng,

Zhang,

Fan

et al. 2024

Animals

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The experiment aimed to investigate the effects of plant polysaccharides combined with boric acid on digestive function, immune function and harmful gas and heavy metal contents in the faeces of fatteners. For this study, 90 healthy crossbred fatteners were selected and randomly divided into five groups: the control group was fed with a basal diet (Con); experimental group I was fed with basal diet + 40 mg/kg boric acid (BA); experimental group II was fed with basal diet + 40 mg/kg boric acid + 400 mg/kg Astragalus polysaccharides (BA+APS); experimental group III was fed with basal diet + 40 mg/kg boric acid + 200 mg/kg Ganoderma lucidum polysaccharides (BA+GLP); and experimental group IV was fed with basal diet + 40 mg/kg boric acid + 500 mg/kg Echinacea polysaccharides (BA+EPS). Compared with Con, the average daily gain (ADG), the trypsin activities in the duodenum and jejunum, the IL-2 levels in the spleen, the T-AOC activities and GSH-Px contents in the lymph node of fattening were increased in the BA group (p < 0.05), but malondialdehyde content in the lymph and spleen, and the contents of NH3, H2S, Hg, Cu, Fe and Zn in the feces and urine were decreased (p < 0.05). Compared with the BA, the ADG, gain-to-feed ratio (G/F), the trypsin and maltase activities in the duodenum and jejunum were increased in the BA+APS (p < 0.05), and the T-SOD activities in the spleen and T-AOC activities in the lymph node were also increased (p < 0.05), but the H2S level was decreased in the feces and urine (p < 0.05). Compared with the BA, the ADG, G/F and the trypsin and maltase activities in the duodenum were increased in the BA+GLP and BA+EPS (p < 0.05), the activities of maltase and lipase in the duodenum of fatteners in the BA+GLP and the activities of trypsin, maltase and lipase in the BA+EPS were increased (p < 0.05). Gathering everything together, our findings reveal that the combined addition of boric acid and plant polysaccharides in the diet of fatteners synergistically improved their growth performance and immune status. That may be achieved by regulating the activity of intestinal digestive enzymes, improving the antioxidant function and then promoting the digestion and absorption of nutrients. Furthermore, the above results reduce the emission of harmful gases and heavy metals in feces and urine.

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“…Because the liver is a central organ that plays a key role in the metabolism of carbohydrates, lipids, and proteins, changes in the liver protein content may reveal general metabolic changes [29]. High enzyme levels typically indicate the degree of injury to the organ that produces the enzyme, rather than reduced liver function [30].…”

Section: Discussionmentioning

confidence: 99%

“…References [30,31] studied the effect of amylase supplementation on liver enzymes and protein concentrations. Similar values were obtained for GOT and AP.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Addition of Humicola Grisea Cellulase to Broiler Chicken Rations for a 21-Day Period

Souza,

Ulhoa,

Silva

et al. 2023

Poultry

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This study aimed to evaluate the addition of liquid cellulose, produced by Humicola grisea, in 21-day-old broiler chickens’ diets. The treatments comprised control rations of corn and soybean meal and rations to which 500 mL/t and 1000 mL/t of cellulase were added. A total of 180 male broiler chickens were used, distributed in a completely randomized design, with three treatments and six replicates. Broiler chicken performance was monitored during the period from 1 to 21 days old. Significant effects were detected for digestibility only between four and seven days old, when a reduced dry matter nitrogen intake was recorded, and for nitrogen digestibility in the broilers fed cellulase-supplemented rations at a dose of 1000 m/L. Among the analyzed digestive organs, only the biometrics of the large intestine were affected significantly at seven days old. The absolute weights of the liver and pancreas and the activities of amylase, alkaline phosphatase, and transaminases were not affected significantly, indicating that cellulase did not affect the metabolism of these organs. No significant effect was detected in the serum for electrolytes, total protein, or alkaline phosphatase. So, the addition of liquid cellulase produced by Humicola grisea did not affect performance and metabolism in 21-day-old broiler chickens.

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Supplemental enzymes and probiotics on the gut health of broilers fed with a newly harvested corn diet

Cited by 4 publications

References 55 publications

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, Harmful Gas and Heavy Metal Contents in Faeces of Fatteners

Evaluation of the Addition of Humicola Grisea Cellulase to Broiler Chicken Rations for a 21-Day Period

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