Supplement with whey protein hydrolysate in contrast to carbohydrate supports mitochondrial adaptations in trained runners

Hansen, Mette Halskov; Oxfeldt, Mikkel; Larsen, Anne E.; Thomsen, Lise S.; Rokkedal-Lausch, Torben; Christensen, Britt; Rittig, Nikolaj; Paoli, Frank Vincenzo de; Bangsbo, Jens; Ørtenblad, Niels; Madsen, Klavs

doi:10.21203/rs.3.rs-36706/v2

Cited by 1 publication

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“…Similarly, protein supplementation has been reported to improve performance and reduce markers of muscle damage during a strenuous one-week training camp in runners compared to an energy-matched carbohydrate supplement [ 8 ], as well as to promote adaptations ( e.g . increased lean mass, muscle oxidative capacity, and performance) in response to long-term endurance training [ 9 , 49 , 50 ]. It must be noted, however, that other authors found no beneficial effect of protein supplementation on performance or recovery indicators during a six-day training camp in professional cyclists [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Pre-sleep protein supplementation in professional cyclists during a training camp: a three-arm randomized controlled trial

Alejo

Montalvo-Pérez

Ojanguren

et al. 2023

Journal of the International Society of Sports Nutrition

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Background The effects of pre-sleep protein supplementation on endurance athletes remain unclear, particularly whether its potential benefits are due to the timing of protein intake or solely to an increased total protein intake. We assessed the effects of pre-sleep protein supplementation in professional cyclists during a training camp accounting for the influence of protein timing. Methods Twenty-four professional U23 cyclists (19 ± 1 years, peak oxygen uptake: 79.8 ± 4.9 ml/kg/min) participated in a six-day training camp. Participants were randomized to consume a protein supplement (40 g of casein) before sleep (n = 8) or in the afternoon (n = 8), or an isoenergetic placebo (40 g of carbohydrates) before sleep (n = 8). Indicators of fatigue/recovery (Hooper index, Recovery–Stress Questionnaire for Athletes, countermovement jump), body composition, and performance (1-, 5-, and 20-minute time trials, as well as the estimated critical power) were assessed as study outcomes. Results The training camp resulted in a significant (p < 0.001) increase in training loads ( e.g . training stress score of 659 ± 122 per week during the preceding month versus 1207 ± 122 during the training camp), which induced an increase in fatigue indicators (e.g. time effect for Hooper index p < 0.001) and a decrease in performance (e.g. time effect for critical power p = 0.002). Protein intake was very high in all the participants (>2.5 g/kg on average), with significantly higher levels found in the two protein supplement groups compared to the placebo group (p < 0.001). No significant between-group differences were found for any of the analyzed outcomes (all p > 0.05). Conclusions Protein supplementation, whether administered before sleep or earlier in the day, exerts no beneficial effects during a short-term strenuous training period in professional cyclists, who naturally consume a high-protein diet.

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