Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin

Abstract

There is a rising trend in the consumption of dietary supplements, especially among adults, with the purpose of improving health. While marketing campaigns tout the potential health benefits of using dietary supplements, it is critical to evaluate the potential harmful effects associated with these supplements as well. The majority of the scarce research on the potential harmful effects of vitamins focuses on the acute or chronic toxicities associated with the use of dietary supplements. Quality research is still required to further investigate the risks of long-term use of dietary supplements, especially the risk of developing cancers. The present review concentrates on studies that have investigated the association between the risk of developing cancers and associated mortality with the risk of dietary supplements. Such an association has been reported for several vitamins, minerals, and other dietary supplements. Even though several of these studies come with their own shortcomings and critics, they must draw attention to further investigate long-term adverse effects of dietary supplements and advise consumers and healthcare providers to ponder the extensive use of dietary supplements.

High Concentrations of Se Inhibited the Growth of Rice Seedlings

“…As a trace element, Se is crucial for numerous biological activities, such as thyroid hormone metabolism, antioxidant defense, immune system strengthening, and prevention of certain types of cancer [ 9 ]. Epidemiological studies have shown a negative correlation between Se intake and mortality from various cancers [ 10 ]. Se is primarily obtained from food sources and some Se supplements, including plants, animals, and certain microorganisms [ 11 ].…”