Suplementação enteral e parenteral com glutamina em neonatos pré-termo e com baixo peso ao nascer

Borges, Maria Carolina; Rogero, Marcelo Macedo; Tirapegui, Júlio

doi:10.1590/s1516-93322008000100003

Cited by 3 publications

(3 citation statements)

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“…Glutamine supplementation has been well documented in the literature for various purposes such as the treatment of diseases associated with dysbiosis 21 , ergogenic effect for athletes 22 , premature infants through enteral diet 23 , low birth weight newborns, and children with serious illnesses 24 . The parenteral administration of glutamine has been used in various conditions that lead to metabolic stress such as dengue, HIV, and, until burn 2 .…”

Section: Glutaminementioning

confidence: 99%

Glutamine and sickle cell disease in Brazilian scenario

Cordovil

2023

Nor. Afr. J. Food Nutr. Res.

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Section: Glutaminementioning

confidence: 99%

Glutamine and sickle cell disease in Brazilian scenario

Cordovil

2023

Nor. Afr. J. Food Nutr. Res.

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“…The glutamine is an amino acid with an increased concentration of blood being especially used by the cells that show high numbers of renovation, like the enterocytes and leucocytes 7,8,19 . In addition, it is released in fetal circulation by placental synthesis and by maternal blood 8,16 .…”

Section: Introductionmentioning

confidence: 99%

“…In addition, it is released in fetal circulation by placental synthesis and by maternal blood 8,16 . However, the objective of this study is to validate the gastroschisis experimental model in rats and evaluate the action of glutamine used during pregnancy over the body weight and the morphometrical changes of the fetuses' intestine.…”

Section: Introductionmentioning

confidence: 99%

Validation of the gastroschisis experimental model and the influence of the mother's diet enriched with glutamine in the fetal morphology

et al. 2014

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PURPOSE:To validate the gastroschisis experimental model in female rats and the effects on the glutamine fetal morphology during pregnancy. METHODS:Twelve pregnant rats Wistar were separated in two groups: Group I (n = 6 rats, 71 fetuses) took glutamine and Group II (n = 6 rats, 75 fetuses) took isocaloric supplementation. At the 18 th day of pregnancy, female rats were taken to hysterotomy and the fetuses which were selected for the act of gastroschisis were partially removed from the womb and by the laparotomy technique, the exclusion of the intestine was done. After that, fetuses were put in the womb cavity again and the rats' abdomen sutured. At the 21 st day of pregnancy, date before delivery, by C-section ordinary animals and the ones with gastroschisis were removed and studied separately.The morphometrical parameters studied were the body weight (PC); the intestine weight (PI); the intestine length (CI) and its relations (PI/PC, PI/CI e PC-PI). RESULTS:The intestine weight (PI) and the intestine length (CI) were different in fetuses with gastroschisis (p<0.05), however no difference between the groups regarding supplementation with glutamine. CONCLUSIONS:The gastroschisis experimental model is valid and reproducible. The nutritional therapy with glutamine did not change the morphometrical parameters. Key words: Gastroschisis. Glutamine. Fetal Development. Rats. Validation of the gastroschisis experimental model and the influence of the mother's diet enriched with glutamine in the fetal morphology

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Effect of Glutamine, Glutamic Acid and Nucleotides on the Turnover of Carbon (δ<sup>13</sup>C) in Organs of Weaned Piglets

Amorim

Berto

Saleh

et al. 2015

Asian Australas. J. Anim. Sci

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Morphological and physiological alterations occur in the digestive system of weanling piglets, compromising the performance in subsequent phases. This experiment aimed at verifying the influence of glutamine, glutamate and nucleotides on the carbon turnover in the pancreas and liver of piglets weaned at 21 days of age. Four diets were evaluated: glutamine, glutamic acid or nucleotides-free diet (CD); containing 1% glutamine (GD); containing 1% glutamic acid (GAD) and containing 1% nucleotides (ND). One hundred and twenty-three piglets were utilized with three pigs slaughtered at day zero (weaning day) and three at each one of the experimental days (1, 2, 4, 5, 7, 9, 13, 20, 27, and 49 post-weaning), in order to collect organ samples, which were analyzed for the δ13C isotopic composition and compared by means of time. No differences were found (p>0.05) among treatments for the turnover of the 13C in the pancreas (T50% = 13.91, 14.37, 11.07, and 9.34 days; T95% = 46.22, 47.73, 36.79, and 31.04 days for CD, GD, GAD, and ND, respectively). In the liver, the ND presented accelerated values of carbon turnover (T50% = 7.36 and T95% = 24.47 days) in relation to the values obtained for the GD (T50% = 10.15 and T95% = 33.74 days). However, the values obtained for the CD (T50% = 9.12 and T95% = 30.31 days) and GAD (T50% = 7.83 and T95% = 26.03 days) had no differences (p>0.05) among other diets. The technique of 13C isotopic dilution demonstrated trophic action of nucleotides in the liver.

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Suplementação enteral e parenteral com glutamina em neonatos pré-termo e com baixo peso ao nascer

Cited by 3 publications

References 50 publications

Glutamine and sickle cell disease in Brazilian scenario

Glutamine and sickle cell disease in Brazilian scenario

Validation of the gastroschisis experimental model and the influence of the mother's diet enriched with glutamine in the fetal morphology

Effect of Glutamine, Glutamic Acid and Nucleotides on the Turnover of Carbon (δ<sup>13</sup>C) in Organs of Weaned Piglets

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