2009
DOI: 10.11606/issn.1679-9836.v88i2p94-102
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Suplementação de creatina: efeitos ergogênicos e terapêuticos

Abstract: A creatina foi descoberta há mais de um século, porém seu uso tornou-se importanteno cenário esportivo a partir dos anos 70. Desde então, o aprofundamento dos conhecimentose dos protocolos de utilização fez desta substância o recurso ergogênico lícito mais estudado eutilizado por atletas atualmente. Os benefícios da suplementação em atletas serviram de modelopara estudo da utilização como adjuvante terapêutico em indivíduos doentes, que apresentamalguma deficiência de síntese e ressíntese de ATP, doenças neuro… Show more

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Cited by 2 publications
(2 citation statements)
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“…1,2 The undeniable documented benefits associated with an excellent safety profile of its use, lead researches to explore Cr as a therapeutic aid in many health and sickness conditions, 3 as recent reviewed by Gualano et al 4,5 In this context, Cr supplementation can possibly counteract the final result of many degenerative diseases, like muscle weakness, atrophy and metabolic disturbances. 4,5 In peripheral arterial obstructive disease (PAOD), the chronic obstruction in blood flow to distal territories due to atherosclerotic process, and its consequence and constant mismatch between oxygen delivery and demand, lead to a progressive disability cycle involving muscle fiber atrophy and denervation, negative muscle metabolism alterations, reduced strength and endurance, impairing general physical fitness capacity, specially walking capacity, in diseased individuals.…”
Section: Introductionmentioning
confidence: 99%
“…1,2 The undeniable documented benefits associated with an excellent safety profile of its use, lead researches to explore Cr as a therapeutic aid in many health and sickness conditions, 3 as recent reviewed by Gualano et al 4,5 In this context, Cr supplementation can possibly counteract the final result of many degenerative diseases, like muscle weakness, atrophy and metabolic disturbances. 4,5 In peripheral arterial obstructive disease (PAOD), the chronic obstruction in blood flow to distal territories due to atherosclerotic process, and its consequence and constant mismatch between oxygen delivery and demand, lead to a progressive disability cycle involving muscle fiber atrophy and denervation, negative muscle metabolism alterations, reduced strength and endurance, impairing general physical fitness capacity, specially walking capacity, in diseased individuals.…”
Section: Introductionmentioning
confidence: 99%
“…De fato, há na literatura muitas evidências de que a Cr promova ganhos indiretos significativos de força e potência muscular, bem como aumento da massa magra e da síntese de proteínas contráteis (KREIDER et al 2017;CAMARA;DIAS, 2009) No estudo de Hunger et al (2009), realizaram a suplementação de Cr durante 8 semanas. Sendo que, nos primeiros 5 dias ofertaram um carregamento de 20g de Cr fracionadas em 4 doses diárias.…”
Section: Creatina E Exercício Físicounclassified