Supine Craniospinal Irradiation Using a Proton Pencil Beam Scanning Technique Without Match Line Changes for Field Junctions

Lin, Haibo; Ding, Xuanfeng; Kirk, Maura; Liu, Haoyang; Zhai, Huifang; Hill‐Kayser, Christine; Lustig, Robert A.; Tochner, Zelig; Both, Stefan; McDonough, James E.

doi:10.1016/j.ijrobp.2014.05.029

Cited by 47 publications

(31 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the effect of patient (re)positioning uncertainties on the dose distribution has not been taken into account in this analysis. In fact, one technique might be more robust than another resulting in smaller detrimental effects on the ideal static dose distribution calculated by the treatment planning system [49][50][51]. Comparing the robustness of the different techniques is part of a future work.…”

Section: Discussionmentioning

confidence: 99%

Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy working group)

et al. 2018

View full text Add to dashboard Cite

Purpose: Conventional techniques (3D-CRT) for craniospinal irradiation (CSI) are still widely used. Modern techniques (IMRT, VMAT, TomoTherapy V R , proton pencil beam scanning [PBS]) are applied in a limited number of centers. For a 14-year-old patient, we aimed to compare dose distributions of five CSI techniques applied across Europe and generated according to the participating institute protocols, therefore representing daily practice. Material and methods: A multicenter (n ¼ 15) dosimetric analysis of five different techniques for CSI (3D-CRT, IMRT, VMAT, TomoTherapy V R , PBS; 3 centers per technique) was performed using the same patient data, set of delineations and dose prescription (36.0/1.8 Gy). Different treatment plans were optimized based on the same planning target volume margin. All participating institutes returned their best treatment plan applicable in clinic. Results: The modern radiotherapy techniques investigated resulted in superior conformity/homogeneity-indices (CI/HI), particularly in the spinal part of the target (CI: 3D-CRT:0.3 vs. modern:0.6; HI: 3D-CRT:0.2 vs. modern:0.1), and demonstrated a decreased dose to the thyroid, heart, esophagus and pancreas. Dose reductions of >10.0 Gy were observed with PBS compared to modern photon techniques for parotid glands, thyroid and pancreas. Following this technique, a wide range in dosimetry among centers using the same technique was observed (e.g., thyroid mean dose: VMAT: 5.6-24.6 Gy; PBS: 0.3-10.1 Gy). Conclusions: The investigated modern radiotherapy techniques demonstrate superior dosimetric results compared to 3D-CRT. The lowest mean dose for organs at risk is obtained with proton therapy. However, for a large number of organs ranges in mean doses were wide and overlapping between techniques making it difficult to recommend one radiotherapy technique over another. ARTICLE HISTORY

show abstract

Section: Discussionmentioning

confidence: 99%

Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy working group)

et al. 2018

View full text Add to dashboard Cite

show abstract

“…This technique could only be used for patients who did not have mobile anterior soft tissue, which could significantly change the range of the lateral beams owing to positioning uncertainties. Once PBS on the gantry became available, treatment plans were developed using a posterior beam to treat the upper nodal volume and matched to the lateral beams inferiorly to treat the lower volume using a smeared match technique described by Lin et al (18). The development of our PBS capabilities led to the treatment of patients with a technique using 2 PBS beams 15 to 30 oblique from the posterior (Fig.…”

Section: Treatment Planningmentioning

confidence: 99%

Initial Report of Pencil Beam Scanning Proton Therapy for Posthysterectomy Patients With Gynecologic Cancer

Lin

Kirk

Scholey

et al. 2016

International Journal of Radiation Oncology*Biology*Physics

Self Cite

View full text Add to dashboard Cite

“…Parallel beam scanning systems are considered to be more challenging and more expensive to provide than divergent beam scanning systems. Therefore, the following points need to be considered in relation to the perceived advantage of parallel scanning systems: To some extent, by forcing optimization functions to minimize entrance dose, modulated scanning optimization can also be used to reduce skin dose. Unlike the technical and dosimetric challenges of field matching with scattering systems, robust treatment planning optimization for scanning systems (see “Advanced Treatment Planning” 2018 (in this issue)) provides simple and effective field matching for both parallel and divergent beam geometries. The degree of beam divergence from parallelism also depends on the applied field size (smaller approaches parallelism) and SAD (greater approaches parallelism) for divergent beams. …”

Section: Current State: Beam Transport Systems and Gantriesmentioning

confidence: 99%

New horizons in particle therapy systems

Farr¹,

Flanz

Gerbershagen

et al. 2018

Medical Physics

View full text Add to dashboard Cite

Particle therapy is rapidly expanding and claiming its position as the treatment modality of choice in teletherapy. However, the rate of expansion continues to be restricted by the size and cost of the associated particle therapy systems and their operation. Additional technical limitations such as dose delivery rate, treatment process efficiency, and achievement of superior dose conformity potentially hinder the complete fulfillment of the promise of particle therapy. These topics are explored in this review considering the current state of particle therapy systems and what improvements are required to overcome the current challenges. Beam production systems (accelerators), beam transport systems including gantries and beam delivery systems are addressed explicitly in these regards.

show abstract

Supine Craniospinal Irradiation Using a Proton Pencil Beam Scanning Technique Without Match Line Changes for Field Junctions

Cited by 47 publications

References 20 publications

Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy working group)

Dosimetric comparison of five different techniques for craniospinal irradiation across 15 European centers: analysis on behalf of the SIOP-E-BTG (radiotherapy working group)

Initial Report of Pencil Beam Scanning Proton Therapy for Posthysterectomy Patients With Gynecologic Cancer

New horizons in particle therapy systems

Contact Info

Product

Resources

About