Supersensitive nanothermometer based on CdSe/CdSxSe1-x magic-sized quantum dots with in vivo low toxicity

Silva, Jefferson F.; Oliveira, Jerusa Maria de; Silva, Wagner F.; Soares, Ana C. Costa; Rocha, Uéslen; Dantas, Noélio O.; Filho, Eurípedes Alves da Silva; Duzzioni, Marcelo; Cofré, Axel Helmut Rulf; Castro, Olagide Wagner de; Anhezini, Lucas; Silva, Anielle Christine Almeida; Jacinto, Carlos

doi:10.1016/j.ces.2022.118153

“…Hence, the temperature‐dependent luminescence and magnetic properties of this SMM can be combined with multiple linear regression (MLR) to improve the relative thermal sensitivity of the dual magneto‐optical thermometer. The data analytics now represents indeed a critical aspect in luminescent thermometry and may provide future improvements in the field, as recently highlighted [69–71] . Although the combination of MLR and distinct temperature‐dependent luminescence readouts have been recently proposed for green fluorescent protein (GFP) and Ag 2 S nanoparticles (by some of us), [30] and in all‐optical thermometry of nanodiamonds with silicon‐vacancy, [72] this is the first example that applies the MLR concept to distinct properties of a particular system (Figure 3).…”

Section: Resultsmentioning

confidence: 99%

“…The data analytics now represents indeed a critical aspect in luminescent thermometry and may provide future improvements in the field, as recently highlighted. [69][70][71] Although the combination of MLR and distinct temperature-dependent luminescence readouts have been recently proposed for green fluorescent protein (GFP) and Ag 2 S nanoparticles (by some of us), [30] and in all-optical thermometry of nanodiamonds with silicon-vacancy, [72] this is the first example that applies the MLR concept to distinct properties of a particular system (Figure 3). As τ(T) is not linear over the whole temperature range (5-45 K, Figure 1c), we propose to apply the MLR methodology considering ln t ð Þ for which a pseudo-linear regime could be identified (12-45 K, Figure S21).…”

Section: Methodsmentioning

confidence: 99%

Luminescent Single‐Molecule Magnets as Dual Magneto‐Optical Molecular Thermometers

Zanella,

Aragon‐Alberti,

Brite

et al. 2023

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Luminescent thermometry allows the remote detection of the temperature and holds great potential in future technological applications in which conventional systems could not operate. Complementary approaches to measuring the temperature aiming to enhance the thermal sensitivity would however represent a decisive step forward. For the first time, we demonstrate the proof‐of‐concept that luminescence thermometry could be associated with a complementary temperature readout related to a different property. Namely, we propose to take advantage of the temperature dependence of both magnetic (canonical susceptibility and relaxation time) and luminescence features (emission intensity) found in Single‐Molecule Magnets (SMM) to develop original dual magneto‐optical molecular thermometers to conciliate high‐performance SMM and Boltzmann‐type luminescence thermometry. We highlight this integrative approach to concurrent luminescent and magnetic thermometry using an air‐stable benchmark SMM [Dy(bbpen)Cl] (H2bbpen=N,N′‐bis(2‐hydroxybenzyl)‐N,N′‐bis(2‐methylpyridyl)ethyl‐enediamine)) exhibiting Dy3+ luminescence. The synergy between multiparametric magneto‐optical readouts and multiple linear regression makes possible a 10‐fold improvement in the relative thermal sensitivity of the thermometer over the whole temperature range, compared with the values obtained with the single optical or magnetic devices.

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“…Temperature is the most common physical quantity in life, thus it is very important for fast and accurate determination of temperature in life and industry. − Conventional thermometers, which rely on various temperature-related physical properties to measure temperature, have the disadvantage of not being able to measure temperature in specific environments (moving objects, high voltage and large current, strong electromagnetic field interference, ultralow temperature, biological fluids, etc. ). − Therefore, various thermosensitive luminescent materials have been developed for noncontact temperature sensing, including organic dyes, , quantum dots, , polymers, − organic–inorganic hybrids, − and rare earth doped materials. − Among them, luminescent coordination polymers (CPs) take the advantages of designability, high sensitivity, and excellent anti-interference, , showing great potential in temperature sensing. ,, …”

Section: Introductionmentioning

confidence: 99%

Fluorescence Thermometers Involving Two Ranges of Temperature: Coordination Polymer and DMSP Embedding

Zhou,

Ren,

Yang

et al. 2023

Inorg. Chem.

1

0

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The measurement of temperature is indispensable in the fields of life, science, and industry. Fluorescence thermometers are attractive to researchers because of their advantages such as noncontact, high sensitivity, fast response, and excellent anti-interference. Here, a new coordination polymer (HNU-76) was synthesized by assembling Zn2+ with the H3TCA ligand, a fluorescent molecule with an AIE behavior, which can be used as a fluorescence thermometer. At 100–210 K, the fluorescence intensity ratio of HNU-76 versus temperature conforms to an Arrhenius-type decay relationship (R 2 = 0.997), which can be the candidate for low-temperature sensing. In order to increase the sensing range, 4-[4-(dimethylamino)styryl] pyndine (DMSP) was successfully embedded on HNU-76, obtaining HNU-76⊃DMSP. The fluorescence intensity of HNU-76⊃DMSP conforms to an Arrhenius-type decay relationship (R 2 = 0.997) at 270–360 K versus temperature. HNU-76 can be used for fluorescence detection at low temperatures, due to the DMSP loading, and HNU-76⊃DMSP can serve as the temperature thermometer in a range of temperatures common. Both materials show good cyclability and have the potential to be used in fluorescence thermometers.

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Luminescent Single‐Molecule Magnets as Dual Magneto‐Optical Molecular Thermometers

Zanella,

Aragon‐Alberti,

Brite

et al. 2023

Angewandte Chemie

1

0

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Luminescent thermometry allows the remote detection of the temperature and holds great potential in future technological applications in which conventional systems could not operate. Complementary approaches to measuring the temperature aiming to enhance the thermal sensitivity would however represent a decisive step forward. For the first time, we demonstrate the proof‐of‐concept that luminescence thermometry could be associated with a complementary temperature readout related to a different property. Namely, we propose to take advantage of the temperature dependence of both magnetic (canonical susceptibility and relaxation time) and luminescence features (emission intensity) found in Single‐Molecule Magnets (SMM) to develop original dual magneto‐optical molecular thermometers to conciliate high‐performance SMM and Boltzmann‐type luminescence thermometry. We highlight this integrative approach to concurrent luminescent and magnetic thermometry using an air‐stable benchmark SMM [Dy(bbpen)Cl] (H2bbpen=N,N′‐bis(2‐hydroxybenzyl)‐N,N′‐bis(2‐methylpyridyl)ethyl‐enediamine)) exhibiting Dy3+ luminescence. The synergy between multiparametric magneto‐optical readouts and multiple linear regression makes possible a 10‐fold improvement in the relative thermal sensitivity of the thermometer over the whole temperature range, compared with the values obtained with the single optical or magnetic devices.

show abstract

Supersensitive nanothermometer based on CdSe/CdSxSe1-x magic-sized quantum dots with in vivo low toxicity

Cited by 5 publications

References 69 publications

Luminescent Single‐Molecule Magnets as Dual Magneto‐Optical Molecular Thermometers

Luminescent Single‐Molecule Magnets as Dual Magneto‐Optical Molecular Thermometers

Fluorescence Thermometers Involving Two Ranges of Temperature: Coordination Polymer and DMSP Embedding

Luminescent Single‐Molecule Magnets as Dual Magneto‐Optical Molecular Thermometers

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