Superovulation of Japanese Black Heifers Treated with FSH-P and FSH-R.

Dose Response to a Single Intramuscular Injection of FSH Dissolved in Polyvinylpyrrolidone for Superovulation in Cows.

“…injection also affected the variability in ova/embryo quality. The findings of this study and previous studies [4,6,18] indicate that PVP is a suitable solvent to prolong the absorption of FSH in a single injection and that a single i.m. injection of 40 mg FSH-R dissolved in PVP was effective for superovulation treatment in Holstein parous cows.…”

Superovulation in cattle: practical aspects of gonadotropin treatment and insemination

“…The more important question is the possible biological effect of the so called FSH/LH ratio. Donaldson et al [19], Beckers [3], Chupin et al [11], Gonzales et al [24], Tribulo et al [67], and Yamamoto et al [79] showed that FSH products with reduced LH content give higher ovulation number, fertilisation rate and embryo quality. It is speculated [29] that "high" LH activities cause luteinisation of follicles, receptor down regulation and premature ovulations.…”

Biotecnologia de embriões: III - Otimização do momento da inseminação artificial em fêmeas bovinas superovuladas, para programas de transferência de embriões

“…Os percentuais médios de embriões transferíveis obtidos neste experimento, apresentaram valores abaixo de 60%, de acordo com as observações de Hahn (1983) e de Benevides Filho (1989). Este fato pode em parte ser explicado pela utilização de FSH-P não purificado, já que o conteúdo de LH acarreta um efeito prejudicial ao sincronismo dos gametas, refletindo-se na fecundação e na viabilidade dos embriões (Donaldson et a/., 1986;Cal Iensen et a/., 1987;Foote & Ellington, 1988;Herrier et a/., 1988;Yamamoto et a/., 1993).…”