Supernumerary parathyroid glands in hyperparathyroidism associated with multiple endocrine neoplasia type 1

d’Alessandro, André Fernandes; Montenegro, Fábio Luiz de Menezes; Brandão, Lenine Garcia; Lourenço, Delmar M.; Toledo, Sérgio de Almeida; Cordeiro, Anói Castro

doi:10.1016/s0104-4230(12)70202-6

Cited by 14 publications

(3 citation statements)

References 21 publications

(25 reference statements)

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“…Most people have four parathyroid glands; this patient had five, meaning that he had one supernumerary parathyroid gland . The reported rate of supernumerary parathyroid glands is around 2.5% to 13% . Studies have shown that SHPT patients undergoing TPTX had an incidence of ectopic parathyroid glands of about 15%, and these glands are mainly distributed around the thymus, esophageal tissue, carotid sheath, and mediastinum .…”

Section: Discussionmentioning

confidence: 86%

“…(8) The reported rate of supernumerary parathyroid glands is around 2.5% to 13%. (21) Studies have shown that SHPT patients undergoing TPTX had an incidence of ectopic parathyroid glands of about 15%, and these glands are mainly distributed around the thymus, esophageal tissue, carotid sheath, and mediastinum. (22,23) All of these glands must be removed from the neck to ensure the efficacy of the surgery, though ectopic or supernumerary parathyroid glands render the surgery much more difficult.…”

Section: Introductionmentioning

confidence: 99%

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Sixty‐Two‐Year‐Old Male Suffering From Uremic Leontiasis Ossea Caused by Severe Secondary Hyperparathyroidism

et al. 2018

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Secondary hyperparathyroidism (SHPT) is a long‐term complication of chronic kidney disease–mineral and bone disorder (CKD‐MBD). SHPT is characterized by hyperplasia of the parathyroid glands and abnormal secretion of parathyroid hormones (PTH), calcium and phosphorous metabolic disorders, renal osteodystrophy, vascular and soft tissue calcification, malnutrition, and other multiple system complications, which can seriously affect the quality of life of the patient and increase the risk of cardiovascular disease and mortality rate. Uremic leontiasis ossea (ULO) is a medical condition only rarely encountered clinically. SHPT causes craniofacial bone deformity accompanied by lesions of the nerve, cardiovascular, respiratory, bone, or other systems within the body. The case discussed here is related to severe SHPT. A 62‐year‐old male patient was suffering from leontiasis ossea, pectus excavatum, vascular calcification, spontaneous bone fractures, and lower limb deformities. He was undergoing hemodialysis and given total parathyroidectomy (TPTX) with autotransplantation (AT). We further analyzed the multivariate therapeutic effects of TPTX on this patient in order to provide clinical data for standardized treatment of individuals with CKD‐MBD. © 2018 The Authors JBMR Plus published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.

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Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Sixty‐Two‐Year‐Old Male Suffering From Uremic Leontiasis Ossea Caused by Severe Secondary Hyperparathyroidism

et al. 2018

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“…Very crucial is the surgeon's experience [11,12]. Before surgery precise imaging diagnostics should be performed to consider the number and location of the affected parathyroid glands.…”

Section: Discussionmentioning

confidence: 99%