Superior Segmental Optic Hypoplasia Found in Tajimi Eye Health Care Project Participants

Abstract

The prevalence of superior segmental optic hypoplasia is about 0.3% in the Japanese population.

Superior segmental optic nerve hypoplasia in youth

“…However, Japanese reports have not always supported this claim, 12,21 and neither did our study results. It may therefore be too early to consider this anomaly as a diabetic complication.…”

Long-term follow-up of superior segmental optic hypoplasia

“…1 The former three characteristics were, however, not detected in some published cases. 1,3 Several authors have noted the superiorly truncated shape of the optic discs by scrutinizing the disc border. 5 This seems to refl ect the small retinal opening in the superior portion and may have more diagnostic value than other inconsistent signs of SSOH.…”

“…This is especially important in Japan, where the prevalence of primary open-angle glaucoma is high: approximately 3.6% of individuals ≥40 years old, 2 about ten times the prevalence of SSOH. 3 The best method to differentiate the two conditions is to confi rm the stability of the disc appearance and visual fi elds over time. However, to the best of our knowledge, no studies have been published showing that the optic discs in eyes with SSOH really remain unchanged over a long time.…”

Differentiation by imaging of superior segmental optic hypoplasia and normal-tension glaucoma with inferior visual field defects only

“…In recent years, A form of segmental optic nerve hypoplasia, called superior segmental optic hypoplasia (SSOH), has been reported in recent years, mainly in Asia [1][2][3][4][5][6][7]. SSOH eyes usually have visual field defect in the lower hemifield corresponding to optic disc hypoplasia of the superior to nasal segment [1][2][3][4][5][6][7].…”

“…SSOH eyes usually have visual field defect in the lower hemifield corresponding to optic disc hypoplasia of the superior to nasal segment [1][2][3][4][5][6][7]. Although SSOH has a much lower prevalence than glaucoma [3,4] and an essentially different pathology from the latter, it should be included in the list of differential diagnoses of normal-tension glaucoma (NTG), especially when the visual field defects are located predominantly in the inferior visual field. In our daily clinical practice, we often see cases in which SSOH is misdiagnosed and treated as NTG.…”