Superficial wound infection does not cause inferior clinical outcome after TKA

Guirro, Pau; Hinarejos, Pedro; Sánchez-Soler, Juan; Leal-Blanquet, Joan; Torres-Claramunt, Raúl; Monllau, Joan Carles

doi:10.1007/s00167-016-4290-z

Cited by 10 publications

(17 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Seven cases of late PJI (0.41%) were diagnosed and underwent two-stage revision arthroplasties, among whom 2 patients had a history of being treated for suspected SII. Our rate of PJI is in concert with recent reported rates (21). Multiple factors affect post-TKA infection rates.…”

Section: Characteristicssupporting

confidence: 83%

“…Mean age in our study population was 64.99 years (SD = 11.49), which is somewhat younger than that of similar studies (21), despite the fact that people here refer for surgery at the latest stages of knee joint destruction. This obvious lower age of TKA candidates in Iran could be due to the Middle-eastern lifestyle which is characterized by high-exion activities such as praying, sitting on the ground and using Iranian toilets which needs squatting.…”

Section: Characteristicscontrasting

confidence: 60%

“…Regarding early detection, the latest consensus on PJI has provided some valuable criteria to diagnose a deep infection (19), but literature on the detection of super cial infection after TKA is not clear (20,21).…”

Section: Introductionmentioning

confidence: 99%

“…Some studies (21) have used the US Centers for Disease Control and prevention (CDC) criteriae for identifying surgical site infections which were de ned by the CDC in 1992 as those occurring within 30 days of surgery (22). CDC criteria although effective in general, are not speci cally designed for post-TKA infections.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Low Post-Arthroplasty Infection Rate is Possible in Developing Countries: Long-Term Experience of Local Vancomycin Use From A High-Volume Tertiary Knee Center in Iran

Tahmasebi

Vaziri

Vosoughi

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Significant research has been carried out for prevention and also early detection of post-TKA infections. Regarding prevention, utilizing intrawound vancomycin powder in TKA surgery has yielded rather contrasting results in the pertinent literature. Regarding early detection, CDC criteria, although effective in general, are not specifically designed for post-TKA infections. Here, we present a 7-year experience of primary TKA in a high-volume tertiary knee center in Iran, during which intrawound vancomycin powder was used as a routine practice at the end of TKA surgeries. Also, new criteriae are proposed to detect suspected superficial post-TKA infections. Methods: This is a retrospective analysis of primary total knee arthroplasties performed in a tertiary knee center, from March 2011 to December 2018, by a single senior knee surgeon. All patients with follow-up periods of less than one year were excluded from the study. All patient received vancomycin (powder, 1gr) before water-tight closure of the joint capsule. Results: Altogether, 1710 patients were included in the study. Patients were mostly women (male to female ratio: 1 to 4), with a mean age of 64.99 (SD=11.49) years. The overall infection rate was 2.16% (37 of 1710 patients), including 5 periprosthetic deep joint infections and 32 suspected superficial wound infections. Of the 32 suspected superficial infections that were treated with a one-week course of oral antibiotics, all reported disappearance of symptoms, but 2 cases returned with late deep infection. All in all, 7 patients (0.41%) underwent two-stage knee arthroplasty due to deep joint infections. Conclusions: Our experience shows that by utilizing intrawound vancomycin for 7 years as a routine practice along with other measures, we were able to reach relatively low rates of deep post-TKA infections. Howbeit, randomized controlled trials are required to clarify the effect of intrawound vancomycin on post-TKA infection rate.

show abstract

Section: Characteristicssupporting

confidence: 83%

Section: Characteristicscontrasting

confidence: 60%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Low Post-Arthroplasty Infection Rate is Possible in Developing Countries: Long-Term Experience of Local Vancomycin Use From A High-Volume Tertiary Knee Center in Iran

Tahmasebi

Vaziri

Vosoughi

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Regarding early detection, the latest consensus on PJI has provided some valuable criteria to diagnose a deep infection (20), but literature on the detection of super cial infection after TKA is not clear (21,22). Some studies (22) have used the US Centers for Disease Control and prevention (CDC) criteria for identifying surgical site infections which were de ned by the CDC in 1992 as those occurring within 30 days of surgery (23). CDC criteria although effective in general, are not speci cally designed for post-TKA infections.…”

Section: Introductionmentioning

confidence: 99%

Low post-arthroplasty Infection rate is possible in developing countries Long-term Experience of local Vancomycin use from a high-volume tertiary Knee center in Iran

Tahmasebi

Vaziri

Vosoughi

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Utilizing intrawound vancomycin powder in TKA surgery has yielded rather contrasting results in the current literature. Furthermore, CDC criteria, although effective in general, are not specifically designed for post-TKA infections. Here, we present a 7-year experience of vancomycin use in primary TKA in a high-volume tertiary knee center in Iran. Also, new criteria are proposed to detect suspected superficial post-TKA infections. Methods: This is a retrospective analysis of primary total knee arthroplasties performed in a tertiary knee center, from March 2007 to December 2018, by a single senior knee surgeon. All patients with follow-up periods of less than one year were excluded from the study. Since March 2011, all patient received vancomycin (powder, 1gr) before water-tight closure of the joint capsule. Comparison was made between this group and historical control subjects (operated from March 2007 to March 2011). Results: Altogether, 2024 patients were included in the study. The vancomycin and the control group included 1710 and 314 cases respectively. Patients were mostly women (male to female ratio: 1 to 4), with a mean age of 65.20 (SD=10.83) years. In the vancomycin group, the rate of suspected SII (1.87%) and PJI (0.41%) was significantly lower than the control group (P= 0.002). Conclusions: Our experience shows that by utilizing intrawound vancomycin as a routine practice along with other measures, we were able to reach relatively low rates of deep post-TKA infections. Howbeit, randomized controlled trials are required to clarify the effect of intrawound vancomycin on post-TKA infection rate.

show abstract

The use of 2-octyl cyanoacrylate as an adjuvant to wound closure in total knee arthroplasty

Liu

Xue

et al. 2021

Arch Orthop Trauma Surg

View full text Add to dashboard Cite

Superficial wound infection does not cause inferior clinical outcome after TKA

Abstract: Therapeutic study, Level III.

Cited by 10 publications

References 35 publications

Low Post-Arthroplasty Infection Rate is Possible in Developing Countries: Long-Term Experience of Local Vancomycin Use From A High-Volume Tertiary Knee Center in Iran

Low Post-Arthroplasty Infection Rate is Possible in Developing Countries: Long-Term Experience of Local Vancomycin Use From A High-Volume Tertiary Knee Center in Iran

Low post-arthroplasty Infection rate is possible in developing countries Long-term Experience of local Vancomycin use from a high-volume tertiary Knee center in Iran

The use of 2-octyl cyanoacrylate as an adjuvant to wound closure in total knee arthroplasty

Contact Info

Product

Resources

About