Superficial mucoceles in cancer patients: a retrospective series from a Stomatology unit

Abstract

Background The aim of this study is to relate all the superficial mucoceles found in a cancer center, described the association with oncological conditions, and discuss its etiology and pathology that we found in the past few years. Material and Methods Sixteen cases of superficial mucocele were retrieved from the patients’ records of the Stomatology Department of the A. C. Camargo Cancer Center, São Paulo, Brazil, and demographic and clinical data were collected from electronic medical records. Results There were 16 patients, 8 patients were men and 8 women, with ages varying from 26 to 70 years old. Superficial mucoceles were observed in patients submitted to head and neck radiotherapy ( n =6), graft versus host disease ( n =4), one associated with oral mucositis related to allogenic bone marrow stem cells transplantation ( n =1), systemic lupus ( n =1), Sjögren’s syndrome ( n =1), oral lichenoid lesion associated with pembrolizumab ( n =1) and no local or systemic inflammatory associated found ( n =2). Conclusions This study reports a series of superficial mucoceles from a single stomatology unit. Most patients had superficial mucoceles secondary to head and neck radiotherapy and graft versus host diseases. However, two patients (12.5%) had mucoceles related to systemic inflammatory conditions (Sjögren’s Syndrome and Systemic Lupus). Key words: Superficial mucocele, oncological treatment, oral lesions.