Supercritical impregnation of cellulose acetate with thymol

Milovanović, Stoja; Stamenić, Marko; Marković, Darka; Ivanović, Jasna; Žižović, Irena

doi:10.1016/j.supflu.2014.11.011

Cited by 80 publications

(74 citation statements)

References 27 publications

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“…This could be result of increased diffusivity in solid matrix and higher carvacrol solubility [21] in the scCO 2 which provide a larger driving force for the impregnation [4]. Similar phenomenon was shown for the SSI of cotton gauze and CA with thymol [3,4]. After the period of fast impregnation in the first few hours of the SSI, gradual decrease of the impregnation rate and equalization of the impregnation yield with the loading capacity of carvacrol in CA (∼60%) followed.…”

Section: Supercritical Impregnation Of Cellulose Acetate Withsupporting

confidence: 61%

“…Steeper slope of impregnation curve in the linear regime indicated faster impregnation rate at higher pressures. This could be result of increased diffusivity in solid matrix and higher carvacrol solubility [21] in the scCO 2 which provide a larger driving force for the impregnation [4]. Similar phenomenon was shown for the SSI of cotton gauze and CA with thymol [3,4].…”

Section: Supercritical Impregnation Of Cellulose Acetate Withsupporting

confidence: 59%

“…Amount of impregnated active substance and porous structure of the substrate (carrier) are of vital importance for controlled drug delivery and its efficiency against target bacterial strains. Amount of impregnated additive depends on complex interactions of ternary system (additivesupercritical fluid-polymer) which are affected by CO 2 pressure, temperature, nature of polymer, and time of its exposure to supercritical fluid [4,7,9]. Previous studies demonstrated that pure scCO 2 had negligible effect on CA morphology and thermal properties [5,8].…”

Section: Supercritical Impregnation Of Cellulose Acetate Withmentioning

confidence: 99%

“…Reportedly, supercritical carbon dioxide (scCO 2 ) can be used to load polymeric carriers with antimicrobial substances [2][3][4][5][6][7][8][9][10][11][12], vitamins [13], drugs [14,15], dyes [16,17], and so on. There are two distinctive mechanisms of SSI.…”

Section: Introductionmentioning

confidence: 99%

“…Its good properties stimulated research focused on the generation of CA structures (membranes, foams, microparticles etc.) that contain bioactive compounds [4,5,14,[28][29][30]. These CA structures can be produced with methods like solvent casting, electrospinning, supercritical phase separation, and so on and used for controlled delivery of additives [14,[28][29][30].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Milovanović

Adamović

Aksentijević

et al. 2017

International Journal of Polymer Science

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Supercritical CO 2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50 ∘ C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6-60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0-33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled delivery applications.

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Section: Supercritical Impregnation Of Cellulose Acetate Withsupporting

confidence: 61%

Section: Supercritical Impregnation Of Cellulose Acetate Withsupporting

confidence: 59%

Section: Supercritical Impregnation Of Cellulose Acetate Withmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Milovanović

Adamović

Aksentijević

et al. 2017

International Journal of Polymer Science

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The use of essential oils in chitosan or cellulose‐based materials for the production of active food packaging solutions: a review

Casalini

Baschetti

2022

J Sci Food Agric

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In recent decades, interest in sustainable food packaging systems with additional functionality, able to increase the shelf life of products, has grown steadily. Following this trend, the present review analyzes the state of the art of this active renewable packaging. The focus is on antimicrobial systems containing nanocellulose and chitosan, as support for the incorporation of essential oils. These are the most sustainable and readily available options to produce completely natural active packaging materials. After a brief overview of the different active packaging technologies, the main features of nanocellulose, chitosan, and of the different essential oils used in the field of active packaging are introduced and described. The latest findings about the nanocellulose-and chitosan-based active packaging are then presented. The antimicrobial effectiveness of the different solutions is discussed, focusing on their effect on other material properties. The effect of the different inclusion strategies is also reviewed considering both in vivo and in vitro studies, in an attempt to understand more promising solutions and possible pathways for further development. In general, essential oils are very successful in exerting antimicrobial effects against the most diffused gram-positive and gram-negative bacteria, and affecting other material properties (tensile strength, water vapor transmission rate) positively. Due to the wide variety of biopolymer matrices and essential oils available, it is difficult to create general guidelines for the development of active packaging systems. However, more attention should be dedicated to sensory analysis, release kinetics, and synergetic action of different essential oils to optimize the active packaging on different food products.

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Zeolite/Chitosan/Gelatin Films: Preparation, Supercritical CO₂ Processing, Characterization, and Bioactivity

Pajnik

Dikić

Milovanović

et al. 2022

Macro Materials & Eng

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Chitosan/gelatin and chitosan/gelatin/zeolite films prepared by solvent casting method are impregnated with a mixture of thymol and carvacrol using a green solvent, supercritical carbon dioxide at 35 °C and 30 MPa, during 18 h. Proposed method enables preparation of biocompatible and biodegradable blends with strong antioxidant and antibacterial activity, whereby amounts of loaded thymol/carvacrol (TC) mixture are in the range from 3.3% to 6%. After initial burst release, both types of films exhibit gradual release of bioactive compounds, with around 72% and 96% of impregnated TC mixture released in water and phosphate buffered saline solution (pH 7.4) during tested period of 10 days, respectively. Results of water vapor transmission rate (>76 g m −2 day −1 ) confirm that prepared composites are suitable for wound dressing application. Thermal analysis shows superior properties of prepared TC loaded films compared to control samples. In addition, mechanical and structural properties, as well as solubility and swelling behavior of the obtained films are investigated in detail.

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Supercritical impregnation of cellulose acetate with thymol

Cited by 80 publications

References 27 publications

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

The use of essential oils in chitosan or cellulose‐based materials for the production of active food packaging solutions: a review

Zeolite/Chitosan/Gelatin Films: Preparation, Supercritical CO₂ Processing, Characterization, and Bioactivity

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Supercritical impregnation of cellulose acetate with thymol

Cited by 80 publications

References 27 publications

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

Cellulose Acetate Based Material with Antibacterial Properties Created by Supercritical Solvent Impregnation

The use of essential oils in chitosan or cellulose‐based materials for the production of active food packaging solutions: a review

Zeolite/Chitosan/Gelatin Films: Preparation, Supercritical CO2 Processing, Characterization, and Bioactivity

Contact Info

Product

Resources

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Zeolite/Chitosan/Gelatin Films: Preparation, Supercritical CO₂ Processing, Characterization, and Bioactivity