Supercritical fluid chromatography/supersonic jet spectroscopy

Supercritical fluid chromatography–supersonic jet spectroscopy: II. Capillary column SFC with a sheath‐flow nozzle

“…An SFC analysis of the sample with flame ionization detection is shown in Figure 4a. Even greater complexity of the sample was evident from a GC-MS analysis (16). An extensive analysis of this SRM was also reported by Wise et al (17).…”

Supercritical fluid chromatography–supersonic jet spectroscopy: I. Microcolumns and direct expansions

“…The primary attraction of direct-expansion SFC-SJS lies in the simplicity of the nozzle. There are no problems in transferring nonvolatile samples out of the nozzle, as there have been in secondary flow experiments (9); and, at least in microhore column experiments, dead volume is not overwhelming. Furthermore, smaller pumps are required to maintain the vacuum than in secondary flow experiments.…”

“…Clear descriptions of SJ theory can be found in review articles by Levy ( 5 ) and Smalley et al (6), but some points are summarized briefly here to aid in the discussion of the work reported in this and a following paper (7). Hayes has also written an informative paper on SJ principles and methodologies as they relate to analytical applications (S), and recently we reviewed chromatographic applications of SJS (9). In the conventional gas-phase SJ approach, sample vapor is seeded into a higher pressure carrier gas, and the mixture is expanded through a small nozzle into a vacuum.…”

“…The analytical utility of SJS was first demonstrated by Hayes and Small and co-workers (10,ll) and Amirav et al (12). We and oiliers later showed that S3 spectra of large, nonvolatile compounds could be obtained by using supercntical fluid carriers ( I [3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Experiments can be carried out either as a direct expansion of the fluid (14,15) or by introducing the effluent from the column into a secondary, noble gas expansion (7,16).…”