Supercritical Fluid Chromatography, Pressurized Liquid Extraction, and Supercritical Fluid Extraction

Comparison of supercritical carbon dioxide and ethyl acetate extraction of alkylresorcinols from wheat and rye

“…It seems to be no superior advantage to use SC-CO 2 extraction compared to using organic solvents for the analysis of AR, from an analytical point of view. However, for large-scale isolation, SC-CO 2 extraction might under some conditions be superior, due to faster extraction and need for less solvent (Henry and Yonker, 2006). There was no difference in AR content or homolog profile in extracts from milled compared to intact grains when extracted with ethyl acetate, which is in line with what was found before by Ross et al (2001).…”

Techniques to extract bioactive compounds from food by-products of plant origin

“…For reasons outlined below carbon dioxide is the main solvent used in this technique especially when the target molecule is apolar. However, supercritical water systems have also been used to extract polar compounds (Henry & Yonker, 2006). The critical point of water is very high (374°C, 22.064 MPa) therefore superheated water cannot be used to extract thermally-labile compounds (Lang & Wai, 2001).…”

“…In addition, mass transfer rates are increased because of high, more gas-like, diffusion coefficients and low viscosity values (Diaz-Reinoso et al, 2006;Herrero et al, 2006). Surface tensions of supercritical fluids are relatively low, which means more delicate compounds remain intact (Henry & Yonker, 2006). A disadvantage of using CO 2 as a solvent is that it is relatively apolar thus for polar analytes a co-solvent such as ethanol is often added to CO 2 (Diaz-Reinoso et al, 2006).…”

Progress in field‐assisted extraction and its application to solid sample analysis

“…PLE, also known as pressurized solvent extraction (PSE) or ASE , is a semi‐automated solvent extraction method that involves extraction using liquid solvents at elevated temperature and pressure for solid and semi‐solid samples. The extraction is performed with solvents at high temperature (up to 200°C) and pressure (200 bar or 20 MPa), the analytes can be effectively extracted with about 50–100 mL solvent within 30–60 min.…”