“…At this regard, benign supercritical CO 2 extraction seems promising as it possesses many desirable features for separating and purifying desired components from natural products and foods. Therefore, a number of recent studies have been contributed to the cholesterol reduction by using supercritical fluid extraction methodology from cattle brain (Vedaraman et al, 2004(Vedaraman et al, , 2008, cow brain (Vedaraman et al, 2005), shrimp (Higuera-Ciapara et al, 2005), pork (Lin et al, 1999), chicken meat (Froning et al, 1994), turtle fish egg (Shen et al, 2008), egg yolk (Bringe, 1997;Froning et al, 1998), butter oil (Mohamed et al, 1998(Mohamed et al, , 2000 and squid oil (Kang et al, 2005). These researches have indicated that supercritical fluid extraction technology holds promise for substantially reducing cholesterol contents and thus offers an alternative to current methods of developing low-cholesterol foods.…”