Supercritical carbon dioxide as a medium for enzymatically catalyzed reaction

Enzymatic synthesis of isoamyl acetate with immobilized Candida antarctica lipase in supercritical carbon dioxide

“…The yield of isoamyl acetate was 100% for 30 days, and then it slowly decreased. Habulin et al found similar results with an immobilized Rhizomucor miehie lipase, reporting a 4% decrease in conversion after one month of treatment [26]. …”