Super-selective ASL and 4D ASL-based MR Angiography in a Patient with Moyamoya Disease

Abstract

Abbreviations ASL Arterial spin labeling CENTRA Contrast-enhanced timing-robust angiography CT Computed tomography DSA Digital subtraction angiography DSC Dynamic susceptibility contrast EPI Echo planar imaging FLAIR Fluid-attenuated inversion recovery GRE Gradient recalled echo ICA Internal carotid artery MRA Magnetic resonance angiography MRI Magnetic resonance imaging TOF Time-of-flight The authors Nico Sollmann and Hans Liebl contributed equally to the manuscript.

Delay of switch from hypo- to hyperperfusion in migraine aura evidenced by arterial spin labeling (ASL): case series and pooled-data analysis

“…Finally, super-selective ASL and 4D ASL-based MR angiography was able to reveal time-resolved ow signals of the distal ICA and predict territorial perfusion and collateral vessels in Moyamoya disease [20].…”

Advances in differential diagnosis of cerebrovascular diseases in magnetic resonance imaging: a narrative review

“…Moyamoya disease can change both overall and local properties of this network with and without major stroke or hemorrhagic damage. Patients often show a suboptimal structural covariance network with decreased integrity and pronounced volume loss, and regional nodal betweenness centrality (a measure of central situation in a graph based on shortest paths) of the bilateral medial orbitofrontal cortices is significantly decreased (79,98,102,103).…”

Non-invasive perfusion territory quantification and time-resolved angiography by arterial spin labeling in a patient with a large right-hemispheric AVM: case report

“…Specifically, wholebrain pseudo-continuous ASL, ssASL, and 4D-sPACK sequences were acquired with labeling of the left and right ICA, using an automated label positioning tool based on TOF-MRA imaging at the neck level [12]. Parameters of these sequences were set in agreement with latest recommendations and as previously described [11,13]. Overall, there was a high visual concordance between DSA and 4D-sPACK regarding the localization and extent of AVM feeders and the identification of the venous drainage (Figs.…”

“…This technique allows delineation of perfusion changes for individual arterial territories without the use of a contrast agent [ 9 ]. More recently, a super-selective 4D ASL-based MRA technique (4D-sPACK) has been introduced, which represents a non-contrast-enhanced, time resolved, dynamic MRA approach for selective visualization of arterial vessels [ 10 , 11 ]. The method demonstrated high diagnostic consensus with DSA in identifying arterial feeders and deep venous drainage of brain AVMs [ 10 ].…”

“…Specifically, whole-brain pseudo-continuous ASL, ssASL, and 4D-sPACK sequences were acquired with labeling of the left and right ICA, using an automated label positioning tool based on TOF-MRA imaging at the neck level [ 12 ]. Parameters of these sequences were set in agreement with latest recommendations and as previously described [ 11 , 13 ].…”